Cell Signaling Assays

Multiplate live-cell analysis system – next generation technology for next-level results  Read more...

Track cell proliferation and viability label-free in a 96-well plate Read more...

Track cell proliferation and viability label-free in a 384-well plate Read more...

R&D Proteome Profiler Antibody Arrays R&D Proteome Profiler Arrays allow for the measurement of multiple proteins in a single sample. These arrays require no specialized equipment, and eliminate the need for multiple immunopre... Read more...

This HTRF kit detects changes of cAMP accumulation in response to Gs coupled GPCR activation or inhibition. Read more...

Cisbio offers a line of three ready-to-use assays for measuring cAMP using HTRF® technology. Each kit is optimized for detecting a specific range of cAMP concentrations to allow fine tuning of assay sensitivity. These kits enable high qual... Read more...

R&D Proteome Profiler Human Phospho-Kinase Array Kit - Human Phospho-Kinase Array Kit for the parallel determination of the relative levels of protein phosphorylation. The kit contains 4 sets of 2 membranes - each spotted in duplicate... Read more...

Millipore's full-length mTOR kinase is now available as part of the KinaseProfiler™ Service. This kinase is the first biologically relevant mTOR to be commercially available. The KinaseProfiler Service offers 264 kinases for selectivit... Read more...

Components of the Upstate (Millipore) Casein Kinase 2 Assay Kit: • Casein Kinase 2 Substrate Peptide (Cat.# 12-330)  • Assay Dilution Buffer I (ADBI) (Cat.# 20-108)  • PKA Inhibitor Cocktail (Cat.# 20-114)  • Magnesium... Read more...

This non-radioactive kinase assay kit is a two-stage peptide phosphorylation/colorimetric detection assay kit. In the first stage, a biotinylated substrate peptide containing tandem repeats of Poly (Glu 4 -Tyr) is incubated with a tyrosine... Read more...

This kit is designed to measure the phosphotransferase activity in a kinase cascade reaction initiated by activated Raf-1. Recombinant unactive MEK1 is the substrate for Raf-1. Once activated by Raf-1, MEK1 can phosphorylate and thereby ac... Read more...

The assay kit is designed to measure B-Raf dependent phosphotransferase activity in a kinase cascade reaction using recombinant MEK1, unactive as a B-Raf substrate. Recombinant MAPK2/Erk2, unactive is phosphorylated and activated by the ac... Read more...

Intended for the assay of recombinant B-Raf (supplied) kinase activity with experimental variables as determined by the user. For assay of B-Raf activity from a cell lysate, we recommend an immunoprecipitation-kinase assay, using anti-B-Ra... Read more...

Intended for the assay of recombinant Raf-1 (supplied) kinase activity, with experimental variables as determined by the user. For assay of Raf-1 activity from a cell lysate, we recommend an immunoprecipitation-kinase assay, using anti-Raf... Read more...

Cisbio Bioassays has developed Cellul'erk, a highly accurate HTRF assay for measuring phosphorylated ERK1/2 in 96-, 384- and 1536-well formats providing for an HTS compatible assay. Features: • Simple assay protocols designed for r... Read more...

G-Protein Coupled Receptors (GPCRs) are common drug targets. Previously, most studies were based on the monomeric model, but this perception of GPCRs is now evolving towards homodimeric , heterodimeric and oligomeric models. To facil... Read more...

Cisbio Bioassays offer a comprehensive cellular platform to develop HTRF® ligand binding assays. Features:   • Single technology and cellular platform for all GPCR assays • Unique non-radioactive ligand binding assays • Miniatu... Read more...

Tag-lite® cell-lines and reagents, a multimodal environment streamlined for GPCR studies. Cellular trans-membrane receptors are high potential therapeutic targets in pharmacological research, among them G-Protein Coupled Receptors (GP... Read more...

A new secondary messenger for Gq coupled receptor investigation. Cisbio’s IP-One assay, based on its proprietary HTRF® technology, is the first HTS immunoassay that can easily detect inositol(1)phosphate (IP1), a stable second messenger... Read more...

The Phospho-mTOR Activation Kit measures phosphorylation of mTOR, a kinase involved in the initiation of ribosome biogenesis and translation. Read more...

The Phospho-AKT Activation Kit measures phosphorylation of the 1, 2 and 3 isoforms of AKT, a key kinase involved in regulation of cell proliferation. Read more...

The Phospho-JNK Detection Kit enables quantitation of phosphorylated Jun N-terminal kinase (phospho-JNK) expression in the nucleus. Read more...

Real-Time qPCR assays for kinases and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray plate, Real-Time qPCR Case, Immersion Fluid, Frame Adhesive and Plate-File CD. Read more...

Real-Time qPCR assays for Signal Transduction and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray plate, Real-Time qPCR Case, Immersion Fluid, Frame Adhesive and Plate-File CD. Read more...

  ADP-Glo™ Kinase Assay is a luminescent kinase assay that measures ADP formed from a kinase reaction; ADP is converted into ATP, which is converted into light by Ultra-Glo™ Luciferase.   The lumines... Read more...