Application Note: Size exclusion chromatography method transfer from a standard HPLC to an Arc HPLC System
24 August 2020

In this application note, Waters demonstrates a size-exclusion chromatography (SEC) method transfer for monoclonal antibody (mAb) analysis from an industry-standard HPLC system to the Arc HPLC System. Comparable retention time, percent area of monomer, high molecular weight species, and low molecular degradants and repeatability were obtained from both systems.