Application Note: Novel extraction techniques with ACQUITY UPLC: Pesticide screening in drinking water
13 August 2019

In recent years, efforts have been diverted to investigate effective screening methods with high resolution Time-of-Flight (ToF) instruments and with the capacity of reaching sub ppb (part per billion) levels. With current single chromatography separation setup and the iniherent low sensitivity of ToF instruments compared to tandem quadrupole MS, this demand is quite difficult to achieve. As such, a new analytical strategy is needed to reach those goals. This application note will discuss the performance of 2D LC-QToF setup for the analysis of pesticide residues in drinking water at sub ppb level.