Application Note: HTS Of Protein-Protein Interactions in Mammalian Cells Using Transfected Cell Arrays
13 October 2017

Investigation of protein-protein interactions (PPI) within cells is essential for the elucidation of biological processes and cellular networks. The two-hybrid system is the most commonly used method for PPI analysis. A high-throughput, cost-effective method for analyzing PPI directly in mammalian cells was established: The cell array-based protein-protein interaction assay (CAPPIA).