Application Note: Flexible Automated Workflow for Kinase Selectivity Profiling using PIPETMAX®
26 October 2017

Kinase profiling is a necessary part of the drug discovery process in order to confirm that small molecule inhibitors are specific to the protein kinase of interest, and to determine whether the inhibitor demonstrates off-target activity. This application note reports a how a ready-to-use Kinase Selectivity Profiling System (KSPS) from Promega Corporation, combined with easy to use automation, signal detection, and data analysis supports a streamlined workflow to enable quick and efficient inhouse kinase inhibitor profiling.