Application Note: Optimization of In-Source Adduct Formation for the Analysis of Digoxin in Human Plasma by LC-MS/MS
9 November 2018

Digoxin is a P-glycoprotein substrate commonly prescribed to treat cardiac arrest and arrhythmias. This poster presents an LC-MS/MS method for sensitive quantification of digoxin in human plasma that could potentially be applied in drug-drug interaction studies, where the levels of digoxin observed in plasma samples may deviate significantly from expected therapeutic levels.

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