Application Note: LC-MS of intact therapeutic monoclonal antibodies using Agilent AdvanceBio RP-mAb
16 July 2021
In this application note, Agilent Technologies analyze multiple therapeutic monoclonal antibodies (mAbs), including an antibody drug conjugate (ADC), using AdvanceBio RP-mAb columns in an LC-MS method. This approach delivered fast analysis times and accurate mass determination of intact mAbs.