Application Note: 1-Click Imaging for Rapid Mycoplasma Analysis and Cell Culture Samples
30 July 2018
Mycoplasma contamination in continuous animal cell cultures has long been known to be a serious problem due to the wide range of mycoplasma induced effects on the cells in culture ranging from modifications to cellular gene expression to signal transduction pathway activation, leading to data that might be equally compromised due to the unintended effects of the Mycoplasma contamination. The source of mycoplasma in biopharmaceuticals can be traced from the raw materials, cell lines and cell cultures used in manufacturing. Early detection therefore allows for fast decision making and corrective action to conserve downstream product integrity.