Application Note: P450 Inhibition Predictor: Validation and Benefits of an Inhibitor Algorithm
7 December 2018
Cytochrome P450 isoform CYP3A4 catalyzes the metabolism of both exogenous and endogenous compounds, and inhibition of this enzyme can result in undesirable toxic effects on the body. This application note demonstrates the verification of the major features of the ACD/Labs P450 inhibitor algorithm.