Reprogramming of Somatic Cells to Pluripotency Under Low O2 Conditions
Available on demand
Induced pluripotent stem cells (iPSCs) are a type of stem cell that are artificially produced from adult somatic cells by forcing the expression of certain genes. Reprogramming of somatic cells to pluripotency has been under investigation since the pioneering derivation of iPSCs was published in 2006 by Nobel Prize winner Shinya Yamanaka. iPSCs have shown great promise in the field of personalized and regenerative medicine. Many advances have been made in improving the time and efficiency in deriving pluripotent cells through optimization of media and reprogramming methods. The effect of the atmosphere in which cells are generated, and specifically the effect of hypoxia on cellular reprogramming, is evaluated in this webinar.
Eppendorf