New Advances in Biotherapeutic Aggregate and Charge Variant Analysis
Available on demand
Antibody charge variants have gained considerable attention in the biotechnology industry due to their potential influence on stability and biological activity. Subtle differences in the relative proportions of charge variants are often observed during routine manufacture or process changes and pose a challenge when demonstrating product comparability. There is steadily increasing need for an analytical method that can be used for high-throughput analysis of a large number of samples to support bioprocesses and formulation development.
In this webinar, Cornelia Vad, Senior Product Manager Analytical HPLC, and Tim Rice, Global Outbound Product Manager, will discuss:
- Agilent’s new 100% bio-inert HPLC system surfaces, which eliminate unspecified surface binding, peak tailing, and low resolution
- How to achieve reliable, accurate, precise quantitation for mAb aggregation and protein analysis
- Using Buffer Advisor software and Ion Exchange columns to enable fast, robust, efficient pH and salt gradient method development for charge variant analysis
For Research Use Only. Not for use in diagnostic procedures.
Agilent Technologies