Label-Free High-Throughput MALDI TOF Mass Spectrometry in Drug Discovery
20 Nov 2017

This presentation will give a current overview of label-free high-throughput MALDI TOF mass spectrometry and its use in drug discovery screening. It will explain the basics of MALDI TOF mass spectrometry and the benefits of label-free screening compared to current labeled approaches. Data presented will focus on enzymes in the ubiquitin system (deubiquitylases, E2/E3 ligases) and protein kinases.

Key Learning Objectives
The basics of MALDI TOF mass spectrometry and the benefits of label-free screening compared to current labeled approaches. The presentation will emphazise on high-throughput screening of biochemical assays, and how ultra-fast MALDI mass spectrometry can be used for high and ultra-high-throughput screening.

Who Should Attend:
People involved in drug discovery and screening; pharma, biotech, CROs and academia. Mass spectrometrists who might want to move into this, or non-mass spectrometric experts who intend to move from labeled to label-free techniques.

Bruker Daltonics