Founded in 2002, ACEA Biosciences, Inc. (ACEA) is a pioneer in the development and commercialization of high performance, cutting edge cell analysis platforms for life science research.  ACEA’s xCELLigence® impedance-based, label-free, real-time cell analysis systems and NovoCyte™ benchtop flow cytometers are used in preclinical drug discovery and development, toxicology, safety pharmacology, disease studies, and basic academic research.

Employing noninvasive microelectrodes in automated high-throughput plate formats, our xCELLigence Real-Time Cell Analysis (RTCA) systems maximize the physiological relevance of data extracted from in vitro cellular assays by enabling label-free, real-time monitoring of cell proliferation, invasion/migration, and morphological change.  By eliminating the time- and labor-intensive steps of traditional methods, RTCA vastly improves efficiency and overall productivity.  Moreover, by continuously providing data on cell growth and morphology in the short (seconds to hours) and long (days to weeks) time regimes, RTCA provides a phenotypic view of cellular behavior at an unprecedented level of detail.  Our RTCA systems operate within standard cell culture incubators and are currently being used worldwide in industrial and academic labs in applications that include, but are not limited to, the following:

  • Cell Invasion and Migration
    • Cancer Metastasis
    • Inflammation
    • Wound Healing
    • Embryo Implantation
  • Cardiac Safety Testing
    • Contractility
    • Electrical Activity
    • Long-term Cardiotoxicity Effects
  • Drug-Mediated Cytotoxicity/Apoptosis
  • Cell-Mediated Cytotoxicity and ADCC
  • GPCR-, NHR-, and RTK-Mediated Cell Signaling
  • Virus-Mediated Cytopathic Effects
  • Endothelial Barrier Function
  • Stem Cell Differentiation
  • Immune Cell Activation
  • Phenotypic Screening
  • Cell Quality Control
  • Cell Adhesion and Spreading
  • Cell Response Profiling: Small Molecule & siRNA
  • Cell-Cell Interactions: Co-Culture

ACEA is also helping to revolutionize the field of flow cytometry by designing and producing high performance, customizable benchtop machines at accessible price points.  By including the below features, ACEA’s line of NovoCyte™ flow cytometers is raising the bar for what is expected of benchtop machines.

  • Up to 3 lasers (13 fluorescence channels & 2 scattering channels)
  • 107 dynamic range in all channels
  • Direct volumetric-based cell counting
  • Exchangeable optical filters
  • Powerful yet intuitive integrated software
  • Auto sampling for multiple tube and plate formats
  • Automatic injection port cleaning
  • Automated fluidics maintenance
  • Automated cleaning and decontamination

Powerful, user-friendly benchtop flow cytometers. ACEA is helping to revoluti...

Label-free, real-time cell analysis in a wireless format. The RTCA iCELLigenc...

Cell invasion and migration measured in real-time. The xCELLigence ® RTCA DP...

Label-free, real-time cell analysis in a 6 x 96-well format. The xCELLigence ...

Cardiomyocyte contractility, viability, and electrical activity measured in real-ti...

Contact ACEA Biosciences, Inc.

6779 Mesa Ridge Road #100
San Diego CA 92121
+1 858 724 0928 x3076
Company Website