RNAi Reagents

High-confidence gene silencing Read more...

Fully automated research stainer for IHC, ISH and emerging tests Read more...

Lipofectamine™ RNAiMAX Transfection Reagent from Invitrogen   Invitrogen Lipofectamine™ RNAiMAX Transfection Reagent is a proprietary RNAi-specific cationic lipid formulation that offers the highest transfecti... Read more...

siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee. NM_005194 - human NM_024125 - rat NM_009883 - mo... Read more...

siRNA designed and modified for greater specificity Read more...

Gene silencing in difficult-to-transfect cells guaranteed Read more...

Compact Research Stainer Read more...

The largest and most validated shRNA collection from the RNAi consortium (TRC). Merck's unique shRNA formats leverage the discovery potential of the trusted and proven TRC shRNA collection. When you partner with them, you ga... Read more...

Trusted TRC (The RNAi Consortium) content with shRNA targting 20,000+ human or 21,000+ mouse genes including TRC 1.5 and 2.0 (unique and validated) add-ons which are exclusive to Sigma Read more...

Easily identify hits from pooled shrna screens Read more...

The MISSION pLKO.1-puro Control Vector is a lentivirus plasmid vector. The vector does not contain an shRNA insert and is useful as a negative control in experiments using the MISSION shRNA library clones. Read more...

The MISSION pLKO.1-puro Control Vector is a lentivirus plasmid vector. The vector does not contain an shRNA insert and is useful as a negative control in experiments using the MISSION shRNA library clones. Read more...

Developed at the Broad Institute, the MISSION ® TRC3 human whole genome pooled ORF library consists of over 17,000 unique ORF clones, encoding for over 14,000 genes used for overexpression screening Read more...

The MISSION TRC3 ORF GFP Control Vector is a lentivirus plasmid vector. The vector contains an ORF insert expressing TurboGFP™, and is useful as a positive (or negative control) in experiments using the MISSION TRC3 LentiORF Library... Read more...

MATra-si Reagent for efficient transfection of siRNA/miRNA as well as Antisense Oligos (ODN) using IBA's Magnet Assisted Transfection technology (MATra). MATra is a very gentle, easy-to-handle, fast and highly efficient technology to t... Read more...

MATra-A Reagent for efficient transfection of plasmid DNA using IBA's Magnet Assisted Transfection technology (MATra). MATra is a very gentle, easy-to-handle, fast and highly efficient technology to transfect cells in culture. All type... Read more...

Test set for comparison of Magnet Assisted Transfection versus Magnet Assisted Lipofection. Including a one-month-rent of a universal magnet plate. Optimized for siRNA transfections. Magnet Assisted Transfection (MATra) is a new, easy-... Read more...

Ambion Anti-miR™ miRNA Inhibitors are chemically-modified, single-stranded nucleic acids designed to specifically bind to and inhibit endogenous miRNA molecules. These ready-to-use inhibitors can be introduced into cells using transf... Read more...

Silencer Pre-Designed siRNAs are Ambion-designed siRNAs available for all human, mouse, and rat gene targets in the RefSeq database. These siRNAs are designed for maximum potency and specificity using a highly effective and extensive... Read more...

Ambion Silencer Select Pre-Designed and Validated siRNAs incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemical modifications to yield siRNA with unrivaled efficacy, potency, and specific... Read more...

Ambion Silencer ® In Vivo Ready siRNAs undergo the additional purification and testing necessary for introduction of siRNA into animals. After HPLC purification and annealing, each siRNA is dialyzed to remove salt, sterile filtered,... Read more...

Abmion Validated GAPDH Positive Control siRNA and non-targeting Negative Control siRNAs are available for human, mouse and rat with the same chemical modifications for enhanced efficacy as in other Ambion Silencer Select siRNAs. Read more...

For the first time, you can obtain the benefits of Ambion Silencer Select siRNAs in a convenient 96- or 384-well plate format, plated to your specifications. These siRNA collections enable medium- and high-throughput analysis of phen... Read more...

Silencer siRNA Libraries are sets of Ambion-designed siRNAs targeting all of the genes in a genome or a particular gene class, making them ideal for pathway analysis and target identification/validation . Most libraries include three ... Read more...

siPORT NeoFX’s lipid-based formulation enables the transfection of siRNA into adherent cells as they are subcultured — without increased cytotoxicity. From start to finish, successful gene silencing experiments can be completed in as littl... Read more...