Zetasizer Nano ZS by Malvern Panalytical

Manufacturer Malvern Panalytical  |  Available Worldwide
4.5
/
5.0
  |  21 reviews
Performance, simplicity, versatility


Zetasizer Nano ZS by Malvern Panalytical product image
Zetasizer Nano ZS
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Average Rating: 4.5
21 Scientists have reviewed this product

5 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


Easy to handle, a lot of potential for different kinds of sample issues.
Rating: 5.0

  • Application Area: DLS and Zeta potential messurements

"Easy to handle instrument that provides a wide spectra of usage. As a newbie you will learn quickly how to take your measurements and after a few runs you will start to learn the mechanics and the possibilities of the machine. The sample preparation is really easy for the zeta sizer. It is highly tolerant to concentration issues and polydispersity. "

Review date: 29 Jan 2018 | Zetasizer Nano ZS

Manufacturer's Response

We are glad that you are enjoying the Zetasizer and we hope that you find it useful in furthering your research.
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Revance



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
The instrument is consistent and results reproducible. Must have for protein work
Rating: 5.0

  • Application Area:Aggregation and thermal stability of protein

"The instrument is easy to use and the support is great. I highly recommend users to attend the seminars that Malvern provides, although this is not necessary to start using the instrument. I would recommend they use a test protein first like BSA, for which lots of data is available from Malvern and others. The Application notes were also very helpful and technical experts were extremely helpful."

Review date: 09 Jan 2018 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Pharmaceutical Research Institute



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Great results; Ease of use could be improved
Rating: 3.7

  • Application Area:Nanoparticle sizing and zeta potential

"It is an effective product, if used properly. The documentation is wonderful, and does a great job of explaining the science behind the equipment. Unfortunately, it's design is not aligned well with usability, as at the lab I worked in, I was the only one who read the manual, but I was also the only one who used it the way the manual described"

Review date: 09 Jan 2018 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Pace Analytical Services Inc. on site at 3M Center



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Super instrument for Nano Particle Analysis - Quick, Accurate and Dependable!
Rating: 5.0

  • Application Area:Polymers and Minerals

"Such an easy instrument to run nano particles in various dispersants with low volumes for size and zeta potential. Easy use of various cells to cover all categories. The auto titration unit is also very efficient in producing pH, Iso Electric and titration results. The Malvern customer service people are just an email away when help or service is needed. This is one our most used and valued particle analyzers in our lab!"

Review date: 09 Jan 2018 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Integra LifeSciences



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Great results!! Easy to use!
Rating: 4.3

  • Application Area:Isoelectric point by zeta potential

"The machine is very easy to use. It is easy to set up a new method with the parameters we use for testing. The old results from previous testing is easily accessible to get. The only thing is that the software, whenever I tried to export an excel file, it would never work. Otherwise, the machine works beautifully and I am happy with the test results I have gotten."

Review date: 09 Jan 2018 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: EnGene Inc.



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Extremely useful for characterization of our product!
Rating: 4.0

  • Application Area:Particle size and zetapotential of nanoscale polyplex

"The instrument offers a broad and extensive number of analytical tools that are very useful in nanoparticle R&D. The instrument and software are very user friendly. Result acquisition, analysis, data review and export are consistent, smooth and effective. Measurements are sensitive and accurate, leading to high quality and reproducible results. Settings/format viewing is easily customization for application needs and SOPs are straightforward to create and use."

Review date: 09 Jan 2018 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: PPG



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Easy and Quick Instrument
Rating: 3.7

  • Application Area:Paritcle size determination; zeta potential

"Able to receive good quality results. Standard is reproducible on a weekly basis. Bad quality samples are given a quality report that explains why the sample may not have worked on the instrument. Easy prep. Quick analysis time."

Review date: 31 Jan 2017 | Zetasizer Nano ZS

Manufacturer's Response

Glad you are finding the quality report useful - we feel it's an important feature of our software.
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: PPG



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
I don't know how I worked without this instrument for so long.
Rating: 5.0

  • Application Area:Particle Size Analysis of Various Coatings

"The Zetasizer Nano ZS streamlines particle size testing better than any other instrument on the market. It is a very simple and user friendly instrument. It is incredibly easy to make adjustments on the fly, and the software keeps all of the data and files extremely organized and quite accessible."

Review date: 31 Jan 2017 | Zetasizer Nano ZS

Manufacturer's Response

Great feedback thanks
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University of Birmingham



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Really useful and reliable. An instrument I can depend on.
Rating: 3.7

  • Application Area:analyze polymeric and mineral microparticles

"Results and further analyses are easy to perform. Results are reproducible. Relevant cuvettes are prone to scratches meaning not efficient to use for long"

Review date: 31 Jan 2017 | Zetasizer Nano ZS

Manufacturer's Response

Good to know - thank you
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Brewer Science Inc



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Good instrument, small software issue.
Rating: 4.0

  • Application Area:Particle size analysis for nanomaterials

"We've had a Malvern Zetasizer Nano ZS for 2 years. Mainly running liquid nanomaterial samples for particle size and zeta potential analysis. The instrument and software is easy to operate. Most results obtained were reliable. One thing that I don't like is sometimes the software could crash at the beginning of the run. It seems got fixed with new updated version."

Review date: 31 Jan 2017 | Zetasizer Nano ZS

Manufacturer's Response

Good to know that Malvern's software release programme is appreciated - Thanks


  • Status:

    Reviewer

  • Member since: 2017

  • Organization: 3M



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
It works well with user-friendly software.
Rating: 5.0

  • Application Area:particle size/zeta-potential analysis

"It works well with user-friendly software. Different tabs provide insight about the data, especially when the data does not seem good. Looking into the correlogram and check the expert advisor does help understanding the problem. Also using the trend tab helps to compare different measurements."

Review date: 31 Jan 2017 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Washington University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Best DLS and zeta potential instrument on the market.
Rating: 4.7

  • Application Area:particle size and zeta potential

"The zetasizer nano ZS gives excellent data and is much easier to use than competitor's instruments. I was blown away by the simple functionaility when I first used the instrument. It is the standard in DLS and zeta potential measurements today."

Review date: 31 Jan 2017 | Zetasizer Nano ZS

Manufacturer's Response

Thanks - that's what we strive for!
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Binghamton University (SUNY)



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great result which is able to lead great papers and research!!!!
Rating: 5.0

  • Application Area:Analyze the nanoparticle samples

"I've been using the Malvern nano ZS for almost over 4 years. It is very well known as DLS (dynamic light scattering). My research is biomolecular imaging with several types of nanoparticles. So, I really need the size and zeta-potential data for my research. As I know, most of the researchers are using Malvern DLS instrument. I've submitted several papers and been working on a patent with this instrument. For the science, the essential is the most important. This instrument is the essential of my research."

Review date: 25 Jan 2017 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: UNTHSC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great instrument
Rating: 5.0

  • Application Area:Analyze drug-loaded nanoparticle formulations

"Our Zetasizer has been imperative in allowing me to analyze my drug-loaded polymeric nanoparticle formulation batches with consistent results. I have looked at particle size and zeta potential and always received good results, that were comparable to similar formulations. Instrument is easy to use and allows for numerous analytical combinations."

Review date: 17 Oct 2016 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Carnegie Mellon University



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
Easy to use, reliable results, many applications
Rating: 4.0

  • Application Area:Nano materials

"Used by many researchers, easy to use, robust instrument"

Review date: 17 Oct 2016 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: UNTHSC



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Easy to use and excellent performance
Rating: 4.7

  • Application Area:Nanoparticle particle size and zeta potential measurment

"It is one of the best product from Malvern. It is so simple to use and the performance is excellent and reproducible."

Review date: 17 Oct 2016 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Takeda



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Simple and reliable
Rating: 4.7

  • Application Area:Evaluation of formulation excipients via zeta potential

"The easiest most reliable instrument. Never breaks. Simple to use. Zeta potential does have a large error margin but for the ease of use and low cost to operate worth the 2 min to set up a run. Backscatter feature is nice for smaller particles that would otherwise not be seen."

Review date: 23 Sep 2016 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: VaxForm



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Great Instrument
Rating: 4.3

  • Application Area:Formulation development

"Easy to use, but could have more technical assistance with setting up parameters for SOPs such as when it might be better to use forward versus backscatter. More expansive refractive index/absorbance preloaded."

Review date: 20 Sep 2016 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Intertek



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
Reproducible results, very trustworthy instrument.
Rating: 3.7

  • Application Area:Contract lab -analyze all types of samples.

"The Nano ZS is user friendly, gives reproducible results, and helps by giving you advice for better sample preparation."

Review date: 20 Sep 2016 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of New Mexico



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Very nice piece of equipment
Rating: 4.7

  • Application Area:particle suspensions

"The instrument produces very reliable data. Performing the measurements as well as the data manipulation is easy and convenient. It can go down to low sizes which was important for my research."

Review date: 17 Sep 2016 | Zetasizer Nano ZS
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Alexandria faculty of medicine



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Worth every $
Rating: 5.0

  • Application Area:Analyze size and charge of nanoparticles

"For years been used in our lab to measure size and surface charge of different nanoparticles as: SLN, liposomes, niosomes, magnetic nanoparticles. Perfectly functioning still. "

Review date: 29 Feb 2016 | Zetasizer Nano ZS
Zetasizer Nano ZS for size, zeta potential, protein mobility and microrheology - Performance, simplicity, versatility.

The world’s most widely used system. It is used for the measurement of the size, electrophoretic mobility of proteins, zeta potential of colloids and nanoparticles, and optionally the measurement of protein mobility and microrheology of protein and polymer solutions.

The Zetasizer Nano ZS is a high performance two angle particle and molecular size analyzer for the enhanced detection of aggregates and measurement of small or dilute samples, and samples at very low or high concentration using dynamic light scattering with ‘NIBS’ optics. The ZSP also incorporates a zeta potential analyzer that uses electrophoretic light scattering for particles, molecules and surfaces, and a molecular weight analyzer using static light scattering.

Using Non-Invasive Backscatter optics (NIBS) it has significantly better performance than systems using 90 degree scattering optics.

In addition, a microrheology option is available for measuring sample viscosity and viscoelastic properties, as well as a Protein Measurement option for protein mobility measurements.


Zetasizer Nano ZS Features:

  • Size measurement from 0.3nm (diameter) to 10 microns using patented NIBS (Non-Invasive Back Scatter) technology.
  • Zeta potential using patented M3-PALS technology.
  • Molecular weight measurement down to 980Da.
  • Microrheology option to measure viscosity and viscoelasticity.
  • Protein size measurement as dilute as 0.1mg/mL (Lysozyme).
  • Sample concentrations from 0.1ppm to 40%w/v.
  • Optional protein calculators, including protein charge, A2, kD, and molecular shape.
  • A ‘Quality Factor’ and ‘Expert Advice System’ gives the confidence of having an expert at your shoulder.
  • 21CFR part 11 software option to enable compliance with ER/ES.
  • Research software option to give access to further features and analysis algorithms for the light scattering specialist.
  • Automation of measurements using an autotitrator option.
  • Optional flow mode capability to enable use as a GPC / SEC size detector.
  • Alternative laser, 50mW at 532nm for samples incompatible with the standard 633nm laser.
  • Optical filter option to improve measurements with fluorescent sample.
  • Temperature range extension option to 120ºC.

Product Overview

Zetasizer Nano ZS by Malvern Panalytical product image

Zetasizer Nano ZS

Manufacturer Malvern Panalytical  |  Available Worldwide

4.5 / 5.0 | 21 reviews