Status:
ReviewerMember since: 2022
Organization: AgBiome
Would recommend to researchers conducting untargeted metabolomics.
Application Area:Metabolomics (targeted and untargeted)
"Easy to use Q-TOF instrument for the qualitative, and quantitative, analysis of metabolites, natural products, and proteins. We are using it to identify biologically active products of interest in complex matrices and it works great. Paired with the Masslynx, Unifi, and Progenesis software."
Status:
Advanced ReviewerMember since: 2019
Organization: NIT Rourkela
it is a high end and excellent instrument for new molecules
Application Area:Synthetic organic chemistry, Mass Calculation
"It's a very intelligent and user-friendly product for the calculation of the mass of organic compounds and biological samples too."
Status:
ReviewerMember since: 2019
Organization: Baxter
Good product
Application Area:Small Molecules for Extractable and leachables
"I am happy with the product and support from Waters was excellent"
Status:
ReviewerMember since: 2020
Organization: Rhodes Pharma
Unstable software and difficult to operate and not reproducible results
Application Area:Small molecule unknown impurity identification in pharmaceutical finished product
"The instrument's software UNIFI is difficult to operate and instable. The software frequently causes EPC failure and disconnection to mass spectrometer. It is also difficult to get vendor's technical support or user training from Waters. The instrument is also difficult to pass precision and sensitivity during qualification. I do not recommend the instrument."
Status:
Advanced ReviewerMember since: 2019
Organization: NIT Rourkela
NMR is the lifeline and HRMS is the backbone for every organic chemist
Application Area:Analysis of mass of organic samples as well as proteins
"This is a piece of high-end equipment and therefore expensive because of its accurate measurements. Its usage is hassle-free and you won't find any difficulties during the operation of this instrument. In addition, the service and the demo given by the company were easy to understand. Overall it's a necessary instrument that should be present in every laboratory."
Status:
ReviewerMember since: 2020
Organization: UNL
Overall, Waters instruments are great to work with.
Application Area:Clinical metabolomics and proteomics
"Waters Xevo G2 XS QTOF is a very powerful and reliable instrument for carrying out high-resolution mass spectrometry based metabolomics study. The ease of doing DIA analysis (MSE) using this instrument greatly increases high-throughput and ease of use. Moreover, as an end-user, the Waters Application group actively helps in discussing method development and troubleshooting."
Status:
Advanced ReviewerMember since: 2021
Organization: CRAPC ALGERIA
Good instrument.
Application Area:Pesticides and organic compounds
"Very useful apparatus. We use an UPLC QTOF, it's very sensitive and reproducible. It maintains the stability of the m/z range with a standard. "
Status:
ReviewerMember since: 2014
Organization: Department of Biochemistry, University of Cambridge
Great results, great instrument.
Application Area:Drug discovery
"The Xevo G2-xs qTOF is very easy to use even for beginners. It's highly sensitive with extremely low limits of detection and with impressive mass accuracy. After care sales by Waters has been perfect with all of the questions and problems that we raised/encountered addressed quickly. It's an expensive instrument but definitely worth its price."
Status:
ReviewerMember since: 2020
Organization: University Of Birmingham
Does the job well.
Application Area:Reliable instrument for fast and reliable analysis of biomolecules
"Great equipment for running fast and reliable experiments. Software is easy to use, but has occasional comms errors."
Status:
ReviewerMember since: 2020
Organization: Sabanci University-SUNUM
Great instrument.
Application Area:Monoclonal antibodies
"It is a necessary tool for advanced analysis of mAbs. It is easy to manage the data with their specialized software. The technical support after purchasing is excellent."
Status:
ReviewerMember since: 2018
Organization: European Commission - DG JRC
A great upgrade to next-generation Q-TOF-MS.
Application Area:Protein and peptide discovery
"Compared to our older generation Synapt G2 HDMS, the Xevo G2-X2 QTof is orders of magnitude more sensitive at a higher mass resolution. For our work looking for contaminant proteins (or peptides) in a complicated matrix, this instrument is capable of progressing our projects to a new level. The instrument also has some new features, like SONAR. We can even use this instrument for semi-quant analysis, although we rely on other MS platforms to do reference measurements where measurement uncertainties are below 2% for ratios."
Status:
ReviewerMember since: 2015
Organization: Novartis
Great results, I love working with this instrument.
Application Area:Metabolites identification
"I find the Xevo G2-XS QToF a quite useful instrument for my routine metabolite identification routine work in drug discovery and development. I can obtain the sensitivity and resolution that I need to accomplish my study. MSe is a powerful data acquisition toll that can give you high quality, comprehensive and accurate mass precursor and fragment ion data just in a single analysis."
Status:
Expert ReviewerMember since: 2015
Organization: Ajinomoto Althea
Awesome machine that will take some time to learn
Application Area:Environmental water quality analysis
"There is some in depth training required to use the instrument. It isn't as simple as stand alone GC units I've used in the past. The capabilities of the instrument are incredible, and it is very neat how the instrument can help identify compounds via its software database."
Status:
ReviewerMember since: 2018
Organization: The National Phenome Centre
They are robust, proven technologies that we can deploy with absolute confidence.
Application Area:Large scale metabolic profiling
"We set out to achieve comprehensive metabolome coverage to enable large scale metabolic profiling. With Waters UPLC-MS instruments, we were able to develop standardized high-throughput methodology, allowing for continuous analysis of large sample sets with unprecedented reproducibility at scale. The systems are capable of 24/7 operation with minimal intervention and without running out of samples."
Status:
ReviewerMember since: 2015
Organization: InVision Biomedical Group
I highly recommend for companies which test water to use QTof MS services
Application Area:leachables and extractables
"High resolution and high mass accuracy benchtop QTof systems from Waters are robust, sensitive and relatively easy to operate and maintain. I believe the time for QTof survey and semiquant instruments is dawning."
Status:
ReviewerMember since: 2015
Organization: InVision Biomedical Group
I highly recommend for companies which test water to use QTof MS services for untargeted screens and highly sensitive accurate mass based detection and semiquantitation of contaminants.
Application Area:Leachables and extractables.
"High resolution and high mass accuracy benchtop QTof systems from Waters are robust, sensitive and relatively easy to operate and maintain. I believe the time for QTof survey and semiquant instruments is dawning."
For the scientist who needs to identify, quantify and confirm the broadest range of compounds in the most complex and challenging samples the Xevo G2-XS QTof provides maximum robustness with no compromise in performance, class-leading real-world quantitative sensitivity, the highest quality, most comprehensive qualitative information, flexibility to adapt to changing needs and is accessible to experts and non-experts alike.