xCELLigence RTCA CardioECR by Agilent Technologies

"Easiest and most reproducible instrument for this experiment type."

"xCELLigence provide an exceptionally diverse pattern of functional endpoints, each with the robustness characteristics required to support drug development process and screening. It is a sophisticated platform with sufficient and accurate recording capacity for key physiological and biochemical changes in the cells. It also allows for functional monitoring of the manufacturing process and label-free assessment of the physiological status of beating cells as well as the detection of both short- and long-term responses to compound exposure."

"I was surprised at how easy it was to use considering the incredible amount of data that the xCELLigence CadioECR obtains. The after analysis was all contained within the software and I was fairly fluent after very minimal training. I guess the only difficulty is that the cells need to grow for several weeks before use and so it is not ideal for infrequent use. Value for money is hard to measure as it is very expensive set up and high cost cells and consumables for a research lab but amazing at what it does and nothing else compares. So, expensive but worth it."

"The ACEA Cardio ECR system is very easy and convenient to use, and allows for very informative readouts in a high throughput fashion. The system has good sensibility and is adequate for a quick and dual evaluation of small molecules that cause changes in beating rhythm and induce arrhythmogenic behaviour and/or cardiotoxicity. The ACEA support team has been stellar in their help setting up the system, training personnel and assisting with data analysis and interpretation."