XBridge™ and ACQUITY UPLC® OST C18 Columns for Synthetic Oligonucleotide Analysis and Purification
• Ion-pair, reversed-phase separation of detritylated oligonucleotides on sub-3 micron particles yields exceptional component resolution. • UPLC® technology increases sample throughput while maintaining necessary oligonucleotide component resolution. • LC/UV and LC/MS methods for enhanced quantitative and qualitative oligonucleotides analyses. • Various XBridge™ OST C18 column dimensions address lab scale purification needs. • 2nd generation hybrid-silica BEH Technology™ particles deliver exceptional column life.
Use of synthetic oligonucleotides for research, diagnostic, and therapeutic applications continues to increase. The availability of 2.5 μm HPLC or 1.7 μm UPLC® technology particles in several column dimensions provides flexibility to meet various LC/UV or LC/MS application needs. Waters' stringent manufacturing and quality control procedures help ensure consistent batch-to-batch and column-to-column performance.