XBridge™ HPLC Columns

XBridge™  HPLC Columns
 4.2/5.0 (22 reviews)

Waters

The XBridge™ column family is designed for maximum method development flexibility. Develop robust methods across the entire pH spectrum using an unparalleled range of mobile phases and temperatur...read more

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Reviews

Josh McGee


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Member since 2014

Organization:
HNC Products Inc.
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RATING: 4.0

  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 13 Mar 2014

Application Area: Cosmetics/Quality Control
XBridge™ HPLC Columns

"We use an Xbridge C18 column for assaying raw material and actives in our Cosmetic products. It is a very useful column for method development because of its broad pH range and peak reproducibility. "

Read 22 reviews

Daniel Denis


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Member since 2014

Organization:
Galderma
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RATING: 4.0

  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 13 Mar 2014

Application Area: Dermatology
XBridge™ HPLC Columns

"I discovered this new HPLC column and it seems to be very promising for the separation of peaks (resolution). "

Tohru IKEGAMI


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Member since 2013

Organization:
Kyoto Institute of Technology
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RATING: 3.0

  • 4 out of 5EASE OF USE
  • 2 out of 5AFTER SALES SERVICE
  • 3 out of 5VALUE FOR MONEY




Review date: 12 Aug 2013

Application Area: hilic separation
XBridge™ HPLC Columns

"The XBridge Amide column is prepared by high end capped silica particles, and it reduces or excludes our cation-exchange interaction when we use it in HILIC mode. HILIC phases are understood as mixed-mode phases, and the retention mechanism is difficult to understand due to its complex nature. In the case of XBridge Amide column, only hydrophilic partition mechanism seems to be important, and it is much easier to understand retention mechanism compared to another non-endo-capped stationary phases. In the case of a column, we do not need any after sales service, but we could find out the separation characteristics via the information from the company. The column is valuable in HILIC separation. It seems to be stable though the degree of hydrophilic nature and is somewhat lower than conventional amide bonded stationary phases. As mentioned above, this stationary phase is valuable to consider."

Carla Grazieli


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Member since 2011

Organization:
UniCAMP
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RATING: 4.3

  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 12 Aug 2013

Application Area: pharmaceutical analysis
XBridge™ HPLC Columns

"Excellent columns for basic compounds separation and high stability. I used to compare with other stationary phases that are without hybrid silica and the results were poorer."

Ritsuko Wakayama


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Member since 2013

Organization:
SHOWADENKO
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RATING: 3.7

  • 3 out of 5EASE OF USE
  • 3 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 08 Aug 2013

XBridge™ HPLC Columns

"The chromatogram is nice especially for the separation of smaller hydrophobic compounds."

Simon Makuc


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Member since 2013

Organization:
Krka, d.d
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RATING: 4.0

  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: pharmaceutical analysis - related substances, assay
XBridge™ HPLC Columns

"We used Xbridge columns for developing methods for assay and related substances. They are very robust and batch to batch reproducibility is excellent. With each column we do over 3000 injections."

Alexey Lapin


Status:


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Member since 2013

Organization:
Euroscreen SA
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RATING: 4.7

  • 5 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: pharmaceutical analysis
XBridge™ HPLC Columns

"In my opinion XBridge columns are one of the best available on the market due to its universality. I am using it widely for analytical separations and (especially) for preparative purpose. The major advantages are: broad pH range; high stability at high pH; high durability and low column bleeding."

Yoachim Vanderheyden


Status:


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Member since 2013

Organization:
Vrije Universiteit Brussel
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RATING: 4.3

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: Column to column comparison
XBridge™ HPLC Columns

"The XBridge Waters columns are very easy to use. I used them in a comparison of different vendors columns. I must note that the after sales service did help me in my research."

Adrienn Matray-David


Status:


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Member since 2013

Organization:
Gedeon Richter
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RATING: 3.3

  • 4 out of 5EASE OF USE
  • 3 out of 5AFTER SALES SERVICE
  • 3 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

XBridge™ HPLC Columns

"For ease of use, the chromatogram is fine and the column is reliable. My group like it. It is easily available and the work time is very long."

Zoran Kitanovski


Status:


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Member since 2013

Organization:
National Institute of Chemistry
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RATING: 5.0

  • 5 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 07 Aug 2013

Application Area: Dicarboxylic acids in atmospheric particulate matter
XBridge™ HPLC Columns

"I used XBridge Amide 3.5 um column for HILIC separation of atmospheric dicarboxylic acids. I found it very reproducible over a large period of time (> 3 months) while being extensively used during initial method development (use of different mobile phase buffers, pHs and organic solvents), method validation and application to atmospheric particulate matter. After more than 1000 injections with proper change of the guard, the analytical column preserved its initial efficiency and gave me the needed selectivity for separation of the various atmospheric acids. The column is still in good shape and operable. No increase of the column backpressure was observed during its use. We are very satisfied with the product and the level of service provided by Waters representatives."

James Murner


Status:


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Member since 2013

Organization:
ATMI
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RATING: 3.0

  • 3 out of 5EASE OF USE
  • 3 out of 5AFTER SALES SERVICE
  • 3 out of 5VALUE FOR MONEY




Review date: 08 Jul 2013

Application Area: pharmaceuticals
XBridge™ HPLC Columns

"Great columns! Good resolution, fair price, good selection. Validation packs are helpful for method validation."

Gregory Rahm Jr


Status:


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Member since 2013

Organization:
Q Laboratories
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RATING: 4.0

  • 4 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 03 Jun 2013

XBridge™ HPLC Columns

"This variety of column was a workhorse for a test that we were conducting; it was robust enough to keep running without much maintenance involved. The column we were using performed very well under the strict time constraints that we were working with."

Vipan Taneja


Status:


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Member since 2013

Organization:
Bristol Myers Squibb
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RATING: 5.0

  • 5 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 28 May 2013

Application Area: Analytical method development
XBridge™ HPLC Columns

"X-bridge columns: Waters very reliable columns for HPLC separations and work very well at a wide range of mobile phase pH conditions, and may be very suitable for pH optimization studies for method development. I would highly recommend these columns to a colleague.  If I was doing a pH optimization study, I would like to know if the column was good/stable over a wide pH range."

King Chan


Status:


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Member since 2010

Organization:
SAIC-Frederick, Inc.
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RATING: 5.0

  • 5 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 28 May 2013

Application Area: high ph buffer
XBridge™ HPLC Columns

"Most of the time it uses formic acid buffer, but there are needs to use high pH buffer like 0.1 % NH4OH. The column performs well and is very stable. If using 2.5 µm particles, consider the XP format as it is cheaper according to the webpage."

Mickey Rego


Status:


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Member since 2013

Organization:
Averica Discovery
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RATING: 4.3

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 28 May 2013

Application Area: Pharma
XBridge™ HPLC Columns

"The columns are helpful in a wide variety of application areas. Products can withstand a wide pH range. They last and are fairly affordable. Have bought several and have yet to have a problem."

Sarah Chen


Status:


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Member since 2013

Organization:
GlaxoSmithKline
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RATING: 5.0

  • 5 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 22 May 2013

Application Area: pharmaceutical analysis
XBridge™ HPLC Columns

"Good, reliable, reproducible. Many methods were developed on this column with good result. It is good for basic conditions, have basic condition method with many injections, do not have column for 2 years and still running.  Good column, highly recommended to others. I like it very much, I will use it for basic conditions in the future."

ANDREW PHELPS


Status:


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Member since 2013

Organization:
METRICS, INC.
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RATING: 4.3

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 15 May 2013

Application Area: Pharmaceutical Development
XBridge™ HPLC Columns

"This column is used for our higher pressure methods and is very consistent. We will continue to use it for future products."

Carol Stein


Status:


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Member since 2011

Organization:
Copperhead Chemical Co
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RATING: 4.0

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 3 out of 5VALUE FOR MONEY




Review date: 08 Apr 2013

Application Area: HPLC
XBridge™ HPLC Columns

"This product is nice because it allows us to increase separation resolution without changing the validated method. The X-Bridge columns are part of Waters new smaller particle size columns. The chemistry of the stationary phase is the same as the 5um columns we have used in the past but packing is now 3.5um. We have just started using the columns so I cannot comment on the shelf life difference."

Kunwar Sanjeev Singh


Status:


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Member since 2010

Organization:
Parabolic Drugs Ltd.
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RATING: 4.7

  • 5 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 5 out of 5VALUE FOR MONEY




Review date: 03 Nov 2012

Application Area: Analytical Research & Development
XBridge™ HPLC Columns

"This is a very rugged column in reversed phase chromatography with a wide pH range. It is an ideal column for method development with maximum flexibility across the entire pH range. This is a very good column for isolation and purification, the high pH stability of XBridge Prep columns allows for purer fractions and increased mass loading for bases. It gives batch to batch reproducibility, consistent results and extended lifetime under even the most demanding conditions. "

Purificacion Fernandez


Status:


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Member since 2011

Organization:
University of Santiago de Compostela
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RATING: 4.3

  • 4 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 10 Aug 2011

XBridge™ HPLC Columns

Lin Ye


Status:


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Member since 2011

Organization:
FDA
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RATING: 4.3

  • 5 out of 5EASE OF USE
  • 4 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 03 May 2011

XBridge™ HPLC Columns

"BEH column separate in a lot of compounds with very nice sharp peaks."

Adrel


Status:


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Member since 2007

Organization:
Lavipharm
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RATING: 4.6

  • 5 out of 5EASE OF USE
  • 5 out of 5AFTER SALES SERVICE
  • 4 out of 5VALUE FOR MONEY




Review date: 16 Dec 2010

XBridge™ HPLC Columns

"excellent performance."

Description

 

The XBridge™ column family is designed for maximum method development flexibility.

Develop robust methods across the entire pH spectrum using an unparalleled range of mobile phases and temperatures. The XBridge™ family of columns is characterized by a strong level of chromatographic performance and confidence. You can achieve robust, rugged methods across the entire pH range of 1-12, simplifying the validation and method transfer process.

For isolation and purification, the high pH stability of XBridge Prep OBD™ columns allows for purer fractions and increased mass loading for bases. XBridge Prep packing materials are fully optimized to deliver maximum efficiency and the highest loadability at the lowest possible back-pressures. These attributes give you the flexibility to choose the best combination of particle size and column dimension to easily purify even the most complex samples.

XBridge columns provide consistent performance and extended lifetime under even the most demanding conditions. Developed with revolutionary technology and the highest levels of manufacturing and quality assurance, they are a trusted solution for your most challenging chromatographic separations.


XBridge™ HPLC Columns Features:

  • Improved pH Stability - Increased column lifetime.
  • Enhanced Column Reliability - Assay ruggedness.
  • Maximised Particle Efficiency - Unmatched peak shape and peak capacity.
  • HPLC to UPLC® Method Transfer
  • Preparative Performance

Column Characteristics:

  • Phase: Amide, C18, C8, HILIC, Phenyl
  • Pore Size: 130 Å
  • Particle Size: 2.5, 3.5, 5, 10 µm
  • Length: 5, 10, 30, 50, 75, 100, 150, 250 mm
  • ID: 1, 2.1, 3, 4.6, 10, 19, 30, 50 mm

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