VP-ITC Isothermal Titration Calorimeter

Manufacturer GE Healthcare
3.3
/
5.0
  |  1 reviews


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Average Rating: 3.3
1 Scientist has reviewed this product

4 out of 5
Ease of use
2 out of 5
After sales service
4 out of 5
Value for money


Rating: 3.3

"It takes a short time to become introduced to the machine, it is easy to handle and it has good accuracy."

Review date: 07 Sep 2011 | VP-ITC Isothermal Titration Calorimeter

The VP-ITC system is an ultrasensitive isothermal titration calorimeter designed for ease-of-use. All functions are operated through software to minimize operator involvement and facilitate fast and accurate analyses without the need for expertise in thermodynamics.

The capabilities of ITC as a technique, combined with the unique performance features of the VP-ITC have made this system the best selling ultrasensitive isothermal titration calorimeter in the world.


Applications include:

  • Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules.
  • Lead optimization.
  • Enzyme kinetics.
  • Assessment of the effect of molecular structure changes on binding mechanisms.
  • Assessment of biological activity.

Why VP-ITC?

  • More than just affinities: Simultaneous determination of all binding parameters in a single experiment - information unobtainable from more limited binding assays.
  • Directly measure sub-millimolar to nanomolar binding constants (102 to 109 M-1). Measure nanomolar to picomolar binding constants (109 to 1012 M-1) using the competitive binding technique.
  • Application versatility: Investigate any biomolecular interaction with high sensitivity.
  • True in-solution technique: No labeling or immobilization required. No buffer restrictions.
  • Easily handles turbid solutions.
  • Easy to use: Unattended operation after sample loading.
  • Complete system: No additional accessories to purchase. No reagents are required.