The VP-ITC system is an ultrasensitive isothermal titration calorimeter designed for ease-of-use. All functions are operated through software to minimize operator involvement and facilitate fast and accurate analyses without the need for expertise in thermodynamics.

The capabilities of ITC as a technique, combined with the unique performance features of the VP-ITC have made this system the best selling ultrasensitive isothermal titration calorimeter in the world.


Applications include:

• Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules.
• Lead optimization.
• Enzyme kinetics.
• Assessment of the effect of molecular structure changes on binding mechanisms.
• Assessment of biological activity.
  

Why VP-ITC?

• More than just affinities: Simultaneous determination of all binding parameters in a single experiment - information unobtainable from more limited binding assays.
• Directly measure sub-millimolar to nanomolar binding constants (102 to 109 M-1). Measure nanomolar to picomolar binding constants (109 to 1012 M-1) using the competitive binding technique.
• Application versatility: Investigate any biomolecular interaction with high sensitivity.
• True in-solution technique: No labeling or immobilization required. No buffer restrictions.
• Easily handles turbid solutions.
• Easy to use: Unattended operation after sample loading.
• Complete system: No additional accessories to purchase. No reagents are required.