VanGuard™ Pre-Columns for UPLC Separations by Waters

Manufacturer Waters
4.4
/
5.0
  |  12 reviews
VanGuard Pre-Columns for UPLC® separations are guard columns that are designed for use with the ACQUITY UPLC® system. These guard columns use an ultra-low volume design (patent pending) that efficiently protects UPLC column performance. This ultra-low volume design does not compromise the UPLC holistic design approach to higher efficiency, greater resolution and increased throughput. Guard columns are typically used in applications where complex, unpredictable and demanding samples are analyze... Read more


VanGuard™ Pre-Columns for UPLC Separations by Waters product image
VanGuard™ Pre-Columns for UPLC Separations
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Average Rating: 4.4
12 Scientists have reviewed this product

4 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2017

  • Organization: UCSF



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great column
Rating: 5.0

  • Application Area: We use it for analitical detection of drugs in human plasma samples using UPLC system to perform PK/

"We always achieve high quality and reproducible results."

Review date: 29 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Dow Chemical



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Product as described.
Rating: 4.0

  • Application Area:protect Column from particulates entering from contaminated samples

"I purchased this column protector for an R& D purpose. This column has done what it was intended to do."

Review date: 25 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: West-Ward Pharmaceuticals



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Works with appropriate column very well.
Rating: 5.0

  • Application Area:Drug Product Analysis

"Used for drug product research. Is suitable for research in our applications as we have ordered vanguard columns in the past as well."

Review date: 15 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: The JM Smucker Co



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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We are happy with results and faster analysis times!
Rating: 4.7

  • Application Area:Analyze caffeine in beverages

"We recently switched our current method over from HPLC to UPLC. We are happy with our results and faster run times. Our run times were 8 -10 minutes and now we see results in 4-5 minutes."

Review date: 12 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Sensient Natural Ingredients



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Fantastic when it works, not so hot for on-site care needs.
Rating: 4.0

  • Application Area:Small molecule separations, high throughput sample analysis

"Waters pre-columns work well at extending the life of the main column on our system. They're easy to use and change out when necessary. The UPLC system is a rock star when it works which is a majority of the time. Waters after market support is great for pre-arranged maintenance, like a PM visit. 3-stars for after sales care as getting a technician on-site for unexpected maintenance needs can take days and we're only a couple hours away from their San Francisco bay area offices."

Review date: 12 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Cayman Chemical Company



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Great result
Rating: 4.3

  • Application Area:performing Reverse Phase HPLC

"We purchased this product few months ago and it worked great for us! "

Review date: 11 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Epa



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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These little guys are great!
Rating: 5.0

  • Application Area:Analyze organic micropollutants in environmental matrices

"These columns are great and have a very long lifetime when properly cared for. They are perfect for protecting our separation columns."

Review date: 11 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Covestro



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great Product and easy to use.
Rating: 4.7

  • Application Area:Industrial Polymers, additives, catalysis & dyes

"Very easy to install. Extends the column life a lot. We routinely using these guard columns and happy with the product."

Review date: 06 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Cidara Therapeutics



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Extends column lifetime
Rating: 4.7

  • Application Area:Analysis of drug product and metabolites in biological matrices. also used in peptide/protein analys

"Easy to install, extends column lifetime by catching the crud. Definitely cheaper to replace than a column when clogged. No noticeable change in chromatography"

Review date: 06 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Regis Technologies



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent design and performance.
Rating: 5.0

  • Application Area:Pharmaceuticals

"No loss of peak performance as compared to no precolumn use. Easy to configure to columns."

Review date: 05 Sep 2017 | VanGuard™ Pre-Columns for UPLC Separations


  • Status:

    Expert Reviewer

  • Member since: 2016

  • Organization: Mitchell Cancer Intitute



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product will always use
Rating: 5.0

  • Application Area:Spe of samples!

"These columns are easy to use and are a great value."

Review date: 20 Jun 2016 | VanGuard™ Pre-Columns for UPLC Separations
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Korea Testing and Research Institute



  • Ease of use
    1 out of 5
    After sales service
    1 out of 5
    Value for money
    1 out of 5
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Rating: 1.0
"I usually analysis aldehydes by using UPLC, so I frequently install the VanGuard column. The result of peak is very sharp whenever I use new column, and when I analysis just 30 samples the column is out of order. So I have to buy new one to analysis the sample. It is really not practical product for me!!!!!"

Review date: 04 Jun 2015 | VanGuard™ Pre-Columns for UPLC Separations

Manufacturer's Response

"The VanGuard needs to be replaced after 30 injections, so from your review it appears the VanGuard is working as intended. It is a replaceable item to protect the column. If it fouls after 30 injections you may be injecting some nasty samples. If you are replacing the ACQUITY column after 30 injections the VanGuard is not working correctly, if that is the case please contact us so we can trouble shoot further."
VanGuard Pre-Columns for UPLC® separations are guard columns that are designed for use with the ACQUITY UPLC® system.

These guard columns use an ultra-low volume design (patent pending) that efficiently protects UPLC column performance. This ultra-low volume design does not compromise the UPLC holistic design approach to higher efficiency, greater resolution and increased throughput.

Guard columns are typically used in applications where complex, unpredictable and demanding samples are analyzed. VanGuard Pre-Columns are the first guard columns specifically designed for routine use at pressures up to 15,000 psi (1,000 bar). The first VanGuard Pre-Columns for UPLC separations will be available with 1.7 µm ACQUITY UPLC BEH C18 chemistry. Additional VanGuard Pre-Columns will be released as they become available.