Ultipor® VF Grade DV50 Virus Filter Cartridges — SBF Junior Style by Pall Life Sciences Products - Biopharmaceutical Division

• Pall Ultipor VF Grade DV50 virus removal filters are a robust means to remove viruses from liquids by microfiltration, while permitting enhanced transmission of proteins. SBF Junior Style pleated membrane mini-cartridges are designed for small-scale qualification and validation studies and for small process batches up to 10 – 20 liters. Typical applications for these easy-to-use direct flow filters include purification of BioPharmaceuticals, plasmaderivatives, protein or serum containing cell-culture media and diagnostic reagents.

Features and Benefits

• 6 log Titer Reduction (TR) for 50 nm viruses
• Robust size exclusion mechanism
• Narrow pore-size distribution
• Easy-to-validate direct flow use
• Linear scale-up to larger batches
• Low protein binding
• Low filter extractables
• 100% integrity-tested
• Pre-use testable with WFI
• Manufactured for use in conformance with cGMP
• ISO 9000 Certified Quality System
• Pharmaceutical P optimized
• Certificate of Test provided
• Validation Guide available
• SBF style also available with 0.2 µm Ultipor® N66, Bio-Inert®, Posidyne®, Fluorodyne® II and Emflon® II media

Quality and Bio-Safety Biological Tests

• Integrity (100% Unit Release Test)
• Correlated to viral (phage) retention

Biological Tests
Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics

Effluent Quality Tests*

• Meets Cleanliness per USP Particulates in Injectables
• Non-Fiber-Releasing per 21 CFR
• Non-Pyrogenic per USP Bacterial Endotoxins (< 0.25 EU/mL)
• Meets Total Organic Carbon and Water Conductivity per USP Purified Water; pH per Sterile Purified Water.

Autoclave Resistance
Lot samples multi-cycle autoclave challenged

* Per lot samples soak or rinse-up flush aliquots