Thermo Scientific™ UltiMate™ 3000 Basic Automated LC System by Thermo Fisher Scientific

"Physically, this is a fairly well designed system, but it can get pretty tall when stacked on a bench. We have the two-pump option, which allows fewer solvents on one system than the other, and isn't ideal. The cycle time between injections is a little longer than I'm used to with other systems. Detector performance (UV-vis and DAD) is fine. Performance as a uHPLC system is good. The Dionex column connectors cope well with high pressures, but can be tricky to remove from a column. You'll need to buy their tubing to plumb in the column, so get a variety of lengths to suit the columns you might use. To check the pump flow rate, you need to provide back-pressure for the pump to work properly, but the manufacturer doesn't appear to be willing to say what back-pressure is required for the pump to meet their specification. The software isn't that user-friendly or intuitive. It has its quirks, some of which I find annoying. The "help" isn't always helpful. "

"Very good system for LC/MS work, it is easy to use and command by using Chameleon software. Maintenance and troubleshooting is quite easy to get around with once you get to know the system well, however the pumps do not offer a constant flow (jumps and falls in pressure, requiring repeated purging and cleaning)."

"I am an expert in nano and capillary LC and the research that I do with the Ultimate(R) 3000 Basic nanoLC System of Thermo Fisher (Dionex) presents exceptional characteristics and the results and configurations offered by the Chromeleon software are amazing. The possibilities to configurate the system are really spectacular and the results obtained present fantastic efficiencies and reproducibility. One of the bad things is the difficultly knowing the software because you need a really intensive course to understand all the functionalities and this causes complications at the start of research. Finally, I think that I would give it a 3.5 out of 5 points because I think that it is possible to improve the system in the near future offering an easy to use software but with the same amazing results."

"Very good and repeatable system, working with capillary system with UHPLC, works very well."

"The 2D setup is not that straightforward. We experienced service issues (which took a long time to fix)."

"This instrument is very easy to use with intuitive software. The system is extremely modular and easy to add or remove equipment. The support is also fairly friendly and knowledgeable."

"The HPLC is really useful to help obtain a phase ratio allowing us to better characterize our polymer columns."

"Very user friendly software, easy to use modules, high sensitivity, very robust. The lab technicians love it. After-sales service is very good and the value for money was really good. There are a lot of detector possibilities, and the connections are very easy to handle."

"This product is very helpful in analyzing our new porous polymer monolith. It is wonderful to be able to use a controlled flow rate to obtain a phase ratio."