Chromatin immunoprecipitation (ChIP) sequencing leverages next-generation sequencing (NGS) to quickly and efficiently determine the distribution and abundance of DNA-bound protein targets of interest across the genome. ChIP-Seq has become one of the most widely applied NGS-based applications, enabling researchers to reliably and simultaneously identify binding sites of a broad range of targets across the entire genome with high resolution and without constraints.
Illumina TruSeq ChIP Sample Preparation Kits provide a simple, cost-effective solution for generating libraries from ChIP-derived DNA that are compatible with Illumina sequencers. Offering the proven data quality and ease of use of TruSeq DNA sequencing, they provide a streamlined workflow that leverages reagent master mixes to minimize pipetting and reduce total assay time. The kits offer more robust multiplex sequencing with 24 unique indexes, allowing researchers to optimize the distribution of sequencing output across samples based on read depth requirements.