Trilencer-27 - Guaranteed Knockdown for siRNA Gene Silencing by AMSBIO

Genomewide coverage against human, mouse and rat 

Trilencer-27 - Guaranteed Knockdown for siRNA Gene Silencing contains Dicer-Substrate duplexes that provide two critical improvements over the use of traditional 21mer siRNA designs.

27mer siRNA takes advantage of the natural processing by Dicer producing 10-fold higher potency and specificity than shorter 21mer RNAi forms. 27mer dicer-substrate duplexes also evade the radar of the mammalian interferon response when expressed in mammalian cells and initiates strong and specific gene silencing.

By its optimal design, Trilencer-27 siRNA has the advantages of improved efficacy and minimal interferon response.

Features and Benefits:

• Genomewide coverage against human, mouse and rat
• 27mer Dicer-substrate duplex--higher potency & minimal interferon response
• Guaranteed* gene knockdown (≥70%)
• 3 gene-specific siRNAs + 1 negative control