Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer by Thermo Fisher Scientific

Manufacturer Thermo Fisher Scientific  |   Model: IQLAAEGAAPFADBMBHQ  |  Available Worldwide
4.4
/
5.0
  |  33 reviews

Test new limits of detection, characterization and quantitation with the latest Tribrid™ mass spectrometer. The Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer is designed to expand performance in advanced proteomics, biopharma and metabolomics applications, including quantitation using isobaric tags, low level PTM analysis, data independent acquisition (DIA), and top down proteomics. The new instrument features enhanced sensitivity resultin... Read more


Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer by Thermo Fisher Scientific product image
Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
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Average Rating: 4.4
33 Scientists have reviewed this product

5 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2019

  • Organization: Cargill



  • Ease of use
    3 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great instrument, the software needs an upgrate to be more intutive and user friendly
Rating: 4.3

  • Application Area: Proteomics

"We receive high quality results with the instrument but the software is a bit confusing to use. I wish the instrument worked with Chromeleon. Xcaliber has too many different nodes to wade through. I also wish the calibration would last longer so we didn't have to calibrate every week."

Review date: 12 Dec 2022 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Maryland Balitmore



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Simple and Efficient
Rating: 4.7

  • Application Area:Proteomics

"The product works well for our mass spec based protein footprinting. Customer service is top tier and the ease of use is appreciated."

Review date: 15 Mar 2022 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Takeda



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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Very sensitive to detect low abundant proteins/peptides.
Rating: 4.0

  • Application Area:Proteomics

"This is high res and high sensitive instrument. I have used it for deep proteome profiling, low abundant antigen peptide identification, low abundant protein identification in high-background matrix such as CSF, MS3 quantification."

Review date: 28 Oct 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Protein Metrics



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Best mass spec.
Rating: 5.0

  • Application Area:Complex protein characterization

"This is the best mass spec on the market."

Review date: 26 Jul 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: ICT Mumbai



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Great result, best instrument for proteomics and metabolomics studies.
Rating: 4.0

  • Application Area:Proteomics and metabolomics

"Orbitrap Fusion is the best instrument for proteomics and metabolomics studies, it gives me high quality and reproducible results. It is user friendly, easy to handle, data acquisition software is very easy to use. Rating for ease of use is worth five stars, after sales care within servicing period is good but after service period over it is a little bit careless about servicing the instrument, Value for money is very costly so most of research centers unable to buy this instrument."

Review date: 24 Jul 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Geneva



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great results, can’t live without this instrument!
Rating: 4.3

  • Application Area:Proteomics

"Incomparable resolution for analysis of very complex samples."

Review date: 16 Jul 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Advanced Reviewer

  • Member since: 2017

  • Organization: University of Nebraska Medical Center



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Qualitative exploration, rapid profiling, and high-resolution quantitation workflows.
Rating: 5.0

  • Application Area:Biological research, proteomics, metabolomics and biopharma

"This new platform incorporates a brighter ion source, segmented quadrupole, improved ion transmission, and improved ETD performance. Fusion Lumos technology excels at the most challenging applications, including low-level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, as well as MSn analysis of small molecules."

Review date: 08 Apr 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Advanced Reviewer

  • Member since: 2020

  • Organization: Biotech



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent.
Rating: 5.0

  • Application Area:Research

"Best for your cost."

Review date: 21 Mar 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: National Institute Of Research And Physical-chemic



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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Great results and easy measurements.
Rating: 3.7

  • Application Area:Analyze organic and inorganic samples

"The service is very effective and powerful. The product is very easy to apply in various fields."

Review date: 20 Mar 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Expert Reviewer

  • Member since: 2021

  • Organization: Sidhee Cement Limited



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Value for money, good quality spectrometer.
Rating: 5.0

  • Application Area:Analysis OF Cement, Clinker and Raw material samples

"Chemical analysis of cement to find out the quality of cement as well as to identify the exact applications for a specific cement type. Using for chemical analysis regularly in our cement manufacturing units for cement quality control, to test quarry sites, and assess intermediate products."

Review date: 20 Mar 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer


  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Laurus Labs Private Limited



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results.
Rating: 5.0

  • Application Area:Analytical development

"Thermo CAD is very good in terms of analysis of UV inactive compounds."

Review date: 20 Mar 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Advanced Reviewer

  • Member since: 2021

  • Organization: Rcb



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product.
Rating: 5.0

  • Application Area:Proteomics, metabolomics and lipidomics

"Data is good and reproducible. Qualitative and quantitative data. User friendly."

Review date: 19 Mar 2021 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Cargill



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Critical for our proteomics discovery and low-abundance quantitation.
Rating: 5.0

  • Application Area:Proteomics

"Excellent sensitivity and resolution for proteomics and small molecule discovery. The use of an Orbitrap instrument in DDA mode has revolutionized our capability for protein discovery and quantitation."

Review date: 24 Dec 2020 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Cargill



  • Ease of use
    2 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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We are very happy with our purchase.
Rating: 3.7

  • Application Area:Proteomics

"The xcaliber software is hard to navigate because there are so many options and different windows. The actual instrument is amazing and delivers high quality results. "

Review date: 11 Jul 2019 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: institute of bioinformatics



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Superb results.
Rating: 4.3

  • Application Area:Analyze proteins derived from tissue samples, proteins, body fluids for bio-marker discovery

"The mass spectrometer Tribrid Orbitrap Fusion from Thermo is very useful for our research purposes. We are using it for proteomic services. Proteins are extracted from tissue samples of patients, body fluids like saliva, serum, urine and also cell lines. Then we digest the proteins into peptides and later on analyze on mass spectrometer. Handling mass spec requires proper training but once you get acquainted with it, you will get to know its worth. It will become easy for you to handle if you spend more time on it. It is sensitive and results are reproducible as well."

Review date: 18 Jun 2019 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Interdyscyplinarne Centrum Nowoczesnych Technologii UMK



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great instrument cant think metabolomics is possible without this instrument
Rating: 5.0

  • Application Area:Intracellular metabolites of algae

"It's highly sensitive with inbuilt compound discoverer library and xcalibur for data acquisition. I recommend others to use this instrument but with a target towards selecting an appropriate library. But the only drawback it's compound discoverer should have the possibility for mzxml format as input."

Review date: 04 Jun 2019 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: teva



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Generate a lot of protein information with confidence.
Rating: 4.7

  • Application Area:Biologics characterization

"It is super fast with productivity to generate a lot of protein information with confidence and limited time."

Review date: 17 Jan 2019 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: the univ. of iowa



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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More functional
Rating: 4.3

  • Application Area:Proteomics for protein identification and quatification

"On site service is good , easy to use, sensitivity is good."

Review date: 18 Dec 2018 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Indiana University Bloomington



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
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Extremely user friendly and gives great data.
Rating: 4.3

  • Application Area:Proteomics

"Thermo Orbitrap Lumos has a high flexibility in setting up instrument with different fragmentation (CID/HCD/ETD/EThcD) methods and different levels of MSn. The templets are extremely useful in designing instrument methodologies. The instrument has very high resolutions and great accuracy with internal lock mass calibration (EASY IC) at each scan, which gives fantastic results. High scan speed enables us to get more ions selected for fragmentation. New version of Xcalibur on Lumos is extremely user friendly."

Review date: 16 Apr 2018 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Novartis



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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fast and furious
Rating: 4.3

  • Application Area:Metabolites identification for LMW compounds

"I came to this instrument 4 months ago, before I was only using QToF for accurate mass. The Lumos is amazing, the data-dependent scan feature offers wide opportunities and speed in our metID analytics. Coupled with microLC, it allows fast data generation for our Discovery in the Biotransformation field."

Review date: 20 Jun 2017 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Texas Biomedical Research Institute



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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This instrument is the way forward to the future of mass spectrometry.
Rating: 4.7

  • Application Area:Do bottoms up unbiased proteomics, SRM, TMT quantification

"We have improved our total protein identification number in TMT labelled samples for a complex cell lysate by 30% which by the way is remarkable."

Review date: 24 Jan 2017 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Southern California



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Nice MS
Rating: 5.0

  • Application Area:Core facility

"I would recommend Thermo MS to others. Easy to use and high quality results."

Review date: 17 Aug 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Stockholm University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Powerful can bring to new discoveries shorter time
Rating: 4.7

  • Application Area:Analysis and characterization of peptides and proteins

"I had the opportunity to receive detailed information about this product during the last Thermo scientific Nordic seminar in Stockholm. It seems that this machine could allow really high quality of the research with a friendly user interface. I would definitely recommend to others. Unfortunately, is out of the budget for the department where I am working. "

Review date: 29 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Advanced Reviewer

  • Member since: 2010

  • Organization: ETC



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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good product
Rating: 3.7
"Good sensitivity for proteomics work and for sites determination. Good for PTM sample after drug treatment "

Review date: 16 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Nottingham, UK



  • Ease of use
    4 out of 5
    After sales service
    2 out of 5
    Value for money
    3 out of 5
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Mass spectrometer with best accuracy.
Rating: 3.0

  • Application Area:For qualitative and quantitative proteome analysis

"It is one of the best and high end mass spectrometer and routinely used in proteome analysis. It is user friendly and robust machine with high throughput. I strongly recommend it for use in quantitative analysis."

Review date: 16 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Element Materials



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
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Good product, easy to use, good results
Rating: 3.0

  • Application Area:Increased detection for residues

"It is easy to use easy to setup and easy to read results. We really like the increased detection for residues. The assay speed is also a plus, very efficient. Multiple users at the lab can easily access programs and results. We would probably recommend it because we do not know any different. "

Review date: 16 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Advanced Reviewer

  • Member since: 2013

  • Organization: SR-UAB



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Reproducible quality of results and data
Rating: 4.3

  • Application Area:its easy to use

"Its a good instrument for producing quality results and easy to use for protocols and data analysis."

Review date: 10 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Indiana University



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Effective and accurate
Rating: 4.0

  • Application Area:Proteomics

"Most effective instrument I have used for quantitative proteomics. Easy to mulltiplex and automate analysis of many samples per day, coupled with a user friendly interface."

Review date: 10 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Aston university



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Definitely worth a new lab
Rating: 3.7

  • Application Area:For metabolomics and proteomics

"It has broadened the coverage of detection for oxidized lipidome in disease samples. The better scanning speed and continuous transmission have improved the detection and quantification range."

Review date: 10 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Osu



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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So far it's a great instrument
Rating: 4.7

  • Application Area:For metabolomics

"High quality results and nice peak separation. Very easy instrument to use, but software is going to take a little getting use to. It is great and I would recommend it to others for use on metabolomics."

Review date: 10 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: GSU



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Love this product
Rating: 5.0

  • Application Area:Glycoproteomics and glycomics

"Fusion is the one always giving the highest resolution for our analysis, it needs only small amount of sample but it can give out a whole lot information."

Review date: 10 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Institute of Microbiology, ETHZ



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Very useful platform for research
Rating: 4.3

  • Application Area:For research

"It is very easy to use and provides high quality of data."

Review date: 10 Feb 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: RA Chem Pharma ltd



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Appropriate instrument for bioanalysis
Rating: 5.0

  • Application Area:Bioanalytical

"Outstanding instrument for bioanalysis and proteomics other research too. Very good service to the customers."

Review date: 29 Jan 2016 | Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer

Test new limits of detection, characterization and quantitation with the latest Tribrid™ mass spectrometer.

The Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer is designed to expand performance in advanced proteomics, biopharma and metabolomics applications, including quantitation using isobaric tags, low level PTM analysis, data independent acquisition (DIA), and top down proteomics. The new instrument features enhanced sensitivity resulting in improved analyte detection, characterization and quantitation, enabling scientists to perform more comprehensive sample analyses faster and with better accuracy than ever before.

 

Novel Orbitrap Fusion Lumos MS Features:

  • Novel high-sensitivity API interface combines a High Capacity Transfer Tube and an Electrodynamic Ion Funnel for increased ion flux and lower limits of detection
  • Advanced Active Beam Guide prevents neutrals and high velocity clusters from entering the resolving quadrupole
  • Advanced Quadrupole Technology combines high selectivity and efficiency of transfer for selected ions symmetrically across the isolation window
  • Advanced Vacuum Technology improves transmission of high molecular weight ions to the Orbitrap analyzer
  • Novel ETD HD—high dynamic range ETD provides significantly increased fragment ion coverage

Established Tribrid MS Features:

  • Tribrid architecture — includes quadrupole mass filter, linear ion trap and Orbitrap mass analyzers
  • Ultrahigh resolving power up to 500,000 FWHM, with isotopic fidelity up to 240,000 FWHM at m/z 200
  • Acquisition rates of up to 20 Hz for both Orbitrap and linear ion trap MSn analyses
  • Full parallelization of MS and MSn analyses with intelligent ADAPT™ (All Dynamically Available Parallelizable Time) technology
  • Synchronous Precursor Selection (SPS) for MS and MSn experiments significantly increases the number of peptides and proteins identified and improves quantitative accuracy when using isobaric mass tags
  • Flexibility of fragmentation — CID, HCD and optional ETD and EThcD available at any stage of MSn with detection in either the Orbitrap or linear ion trap detector enables detailed structure determination of metabolites, glycans and other small molecules
  • Universal Method provides maximal peptide identifications without method optimization for samples of unknown concentration, reducing sample and instrument time requirements for routine peptide identifi cation experiments
  • Intuitive and flexible drag-and-drop user interface simplifies method development and enables unique and complex workflows
Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer by Thermo Fisher Scientific news thumbnail
Editorial Article
Top 10 technology launches at ASMS 2022
15 Jun 2022

Product Overview

Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer by Thermo Fisher Scientific product image

Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer

Manufacturer Thermo Fisher Scientific  |  Available Worldwide

4.4 / 5.0 | 33 reviews