Thermo Scientific Orbitrap Elite Hybrid Mass Spectrometer
|You Seok Hwang|
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Member since 2011
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"Powerful Analytical Tools from small molecules to macromolecules. Coupled with 2D nano LC, this instrument can offer ultimate solutions to identify, quantify, and it enable us to do analysis with limited sample amount. The drawbacks are --> need software improvements in LC integration and it is expensive."
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Member since 2012
The Max Planck Institute of Biophysics
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"We bought the Orbitrap Elite as our main MS platform for analysing complex protein mixtures in a bottom-up UPLC-MSn workflow. In our hands, the Orbitrap performs as expected: High mass-accuracy (and stability), fast MSn cycles and high dynamic range and sensitivity. We are using our Orbitrap Elite 24/7, and that brings me to the only downside: Our machine needed extensive repairs in the first nine months after purchase, which, even though Thermo resonded quickly and actively tried to solve the problems as fast as possible, led to downtimes of about 8 weeks in total. That being said - the results we get are excellent. We would buy it again."
Thermo Scientific* Orbitrap Elite is the industry leading high performance hybrid mass spectrometer combining the next-generation high-field Orbitrap analyzer with the latest dual pressure linear ion trap, Thermo Scientific* Velos Pro.
The high-field Orbitrap analyzer increases speed, sensitivity and dynamic range to dig deeper into your samples. The ultra-high resolution provides certainty in analytical results by enabling molecular weight determination for intact proteins and in-depth analysis of isobaric species.
Generation II ion optics with novel neutral blocking technology and Velos Pro* detection system increases the robustness and quantitation capabilities.
- Novel high-field Orbitrap analyzer
- Resolving power > 240,000 FWHM
- Advanced signal processing
- Multiple fragmentation techniques: CID, HCD and optionally ETD
- Parallel MS and MSn analysis
- Velos Pro ion trap generation II ion optics with neutral blocking technology increase robustness
The high-field Orbitrap analyzer increases speed, sensitivity and dynamic range to dig deeper into your samples. The ultra-high resolution provides certainty in analytical results by enabling molecular weight determination for intact proteins and in-depth analysis of isobaric species. The unsurpassed resolution of the system is especially useful when dealing with complex and low abundance samples, in applications such as proteomics, metabolomics and lipidomics.
The Orbitrap Elite hybrid MS can perform a wide variety of experiments from in-depth discovery based experiments to comprehensive qual/quan experiments. The availability of multiple fragmentation techniques (CID, HCD and optional ETD) offers a new level of versatility and performance for the most challenging research applications.
Application notes and news
- Identifying Differential Proteins in Hepatocellular Carcinoma Using MS
- Multi-Mycotoxin Screening and Quantitation Using UHPLC, High Resolution and Accurate Mass
- Metabolite Profiling and Identification Employing High Resolution MS Strategies and Dedicated Software
- Thermo Fisher Scientific and Immundiagnostik Developing Mass Spectrometry-Based Clinical and Research Tools