Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi by Thermo Fisher Scientific

Manufacturer Thermo Fisher Scientific  |   Model: ND-ONE-W
4.7
/
5.0
  |  26 reviews
Powerful auto-range pathlength technology facilitates accurate measurements for concentrated samples with no need for dilutions


Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi by Thermo Fisher Scientific product image
Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
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Average Rating: 4.7
26 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


NanoDrop one is such a Great instrument, I can't live without it.
Rating: 5.0

  • Application Area: Measure DNA

"Great product, we use it every day, vital product to measure DNA."

Review date: 19 Mar 2018 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University of Florida



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Easy to use, indispensable in any molecular biology lab.
Rating: 4.7

  • Application Area:Nucleic acid quantitation

"The Nano Drop One is very easy to use; however it has some automatic steps where we would prefer that the machine waited for the user to initiate the next step. Our first instrument was bad-out-of-the-box so there was some delay while it was returned etc. Before we had a working replacement. Fisher staff were great in handling the replacement process."

Review date: 15 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Poseida Therapeutics



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Provides data quickly and reliably
Rating: 5.0

  • Application Area:DNA quantification

"Very easy to use machine that initially had a few software bugs but is now working fine"

Review date: 15 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: nanoComposix



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
This instrument is incredibly valuable and saves time and lessens antibody waste.
Rating: 5.0

  • Application Area:Assay development

"This instrument is incredibly valuable and saves time and lessens antibody waste."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Cornell University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Great instrument to have in the lab!
Rating: 4.7

  • Application Area:RNA/DNA quality.

"This instrument has been extremely efficient and effective. There are many options to choose from that allow for easy of use. I have confidence that if I need it for applications other than what I am currently using it for, I will be able to do so with the same ease. Additionally, I had one problem with the software but that issue was easily resolved with the support team."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: akhattri@bsd.uchicago.edu



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Very helpful in our lab. Great instument
Rating: 4.7

  • Application Area:We use it to analyze DNA and RNA samples

"We have used the NanoDrop One for about one and half years and we are very happy with it. Using it is very easy and you almost don't need any guidance. The UI is also very straightforward and self-explanatory. In addition the services is also very prompt"

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Saint Louis University School of Medicine



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
A real workhorse that saves time and sample!
Rating: 4.7

  • Application Area:Quantitation of RNA, DNA and proteins; also to determine dye incorporation

"The main advantage of the NanoDrop is that it requires a very small (2-3uL) of sample, while still maintaining a broad dynamic range and sensitivity relative to a conventional spectrophotometer. You can measure one sample at a time or purchase the 96-well version that measures a plate at at a time. The only weakness of the system is the software is some what limited; for instance, you can not obtain concentration of protein if the extinction coefficient is known. Of course, you can calculate it yourself from the the A260. Other than some minor inconveniences, this is a workhorse in our department."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Columbia university/pharmacology Dept.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
we use it every day.
Rating: 5.0

  • Application Area:DNA consentration

"Very effective, convenient, fast, easy to use and save samples."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: The Ohio State University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Reliable instrument, quick service, convenient.
Rating: 4.7

  • Application Area:Quantitation of protein, nucleic acids and cellular density

"The instrument is easy to use and handle . The results are reproducible for the most part. We do not use the pedestal for cells or protein assays. We rely on the cuvette for those. In built programs for generating standard curves are very handy. Within a month of purchasing the instrument we had issues with inconsistent and overestimated absorbance values. The customer care was quick to fix it for us, and provided us a with a loan instrument during that time. Never had a problem since. I really appreciate that we can use the touchscreen tablet with gloves on. Since it comes with a tablet, it saves us a lot in terms of money and space that would be taken up by a computer for use with other UV-Vis instruments."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University at Buffalo



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Great for use in biology student labs
Rating: 4.0

  • Application Area:Measure concentrations of DNA and RNA

"We use the Nanodrop One in our undergraduate biology lab courses. Each semester they are used by ask many as 300 students. We believe that the accuracy and consistency of the readings is more than adequate for use in a student lab. The students find the Nanodrop easy to use and do not make many mistakes while using it. Since the student preps are sometimes "dirty", the Nanodrop is helpful in letting them know that their sample may be contaminated and what the contaminates may be."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi


  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Case Western Reserve University



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Nanodrop is still best option for membrane protein quantification
Rating: 4.3

  • Application Area:Purified Protein quantification

"For standard A280 measurements, the product works fine. We use on daily basis to quantify membrane proteins -- Measurements are replicable, but tend to be only qualitative measures (as are most other low volume spectrophotometric measurements). However there are major issues with utilization of the cuvette measurement; namely an inability to blank with anything other than water. Doing Bradford or A600 measures generates an error with the blank. Furthermore, we purchased with the cuvette so that media and dye would not be used on the nanodrop pedestal portion of the machine. This being said the nanodrop is still the best commercial option for quantifying membrane proteins but i would counsel against purchasing with the cuvette."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: NIST



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Well, this is my favorite equipment in lab (PS: we have a lot of equipment in lab ;)
Rating: 5.0

  • Application Area:Measure Nucleic Acids etc...

"We have been using a NanoDrop since the beginning (I don't remember the beginning - could be BC...) and with the all new One C, NanoDrop moved it to the next level. It is so easy to use, takes just seconds to run your samples after you turn your device on... I don't think that I need to talk about the reproducibility and sensitivity of any Nanodrop, everyone knows. But this one has a wonderful user interface. Together with the PC viewer, the graphs are ready to use on your publications. I still could not manage to set up the wifi because we are working in a strictly safe governmental facility with high internet safety, but I will find a way to do this too. I am sure that will also be fancy :) I definitely suggest this little cute guy to anyone who is working with DNA, nucleic acids, bases etc... wherever you need a spectrometric analysis... You will see that you got more than every penny you spent..."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University of Washington Medical Center



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great result, and fast
Rating: 5.0

  • Application Area:DNA, RNA Quant

"It is easy to use, and understand, straight forwards. user friendly and give us a high quality quant for DNA."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: IDPH - Springfield



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Absolutely love this instrument , its usability, touchscreen, and upload to the cloud
Rating: 5.0

  • Application Area:Analysis of nucleic acids and protein from isolated pathogens for use RT-PCR, qPCR, and Immunoblotti

"This product is awesome, we use it on a daily basis. Even novices in my lab find the the instrument very easy to use as it walks you through the entire quantification process. In addition, I love the fact that it has a really small footprint in my lab. I also have a Nandrop 2000C which, while works well, has now fallen by the wayside due to the sheer ease of use with the NanoDrop ONE C. I honestly couldn't imagine my lab without this little gem."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: vivoPharm



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Good purchase
Rating: 4.3

  • Application Area:Confirm dose concentrations for proteins and nucleic acid

"Very user friendly. Has more functionality then we need but is nice to have for future."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University of Georgia



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
One instrument, so many applications!
Rating: 4.7

  • Application Area:Check DNA and RNA quality and quantity, assess cell culture OD, enzymology, protein quantification

"I love our NanoDrop! It is nice to only have one instrument taking up space that can do so many things. I use it almost every day to either quantify DNA or RNA and check ODs of cells. I have also found the Bradford settings really helpful and straightforward for quantifying protein when I have occasionally needed to do that and I was even able to calculate enzyme activity using the enzymology program it has. My only complaint about the instrument is that occasionally it "freezes"; however, this tends to be resolved with the faithful "turn it off and back on again" solution."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: St. Jude Children's research hospital



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Good one but the previous one was better
Rating: 4.0

  • Application Area:DNA and Protein

"The nanodrop is one of the most used instruments in my lab. It is almost used everyday sometimes several times a day. We use it for measuring DNA, RNA and Protein at absorbance 280 nm. I liked the previous nanodrop better that had a computer attached to it and it was more robust. This one with the tablet crashes a lot and we have restart it often."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Montclair State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Best for my applications
Rating: 5.0

  • Application Area:Absorbance spectra of natural drug precursors for fluorescence measurements, BioAssays based on abso

"For my applications everything is great especially combination of nanodrop and standard cuvette capabilities. As an idea for further development I'd suggest light guides for Abs measurements in biological objects with non-standard shapes like for example jellyfish"

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Kanyos Bio



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    3 out of 5
Major assets to our lab
Rating: 4.0

  • Application Area:sample concentrations

"This nanodrop is very effective and reliable. I had no issues with it."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Emory University Hospital HLA Laboratory



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
We love it!
Rating: 5.0

  • Application Area:DNA concentration readings

"We love the Nanodrop One. We love that it is stand alone - no separate computer needed. We love that it initializes and then we can just blank it. We do need to print from it sometimes, so we would like it if it could be linked to a printer. Currently - we work around that by using a memory stick to transfer the data to a computer."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: MMRL



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Fast Accurate and reproducible results
Rating: 4.0

  • Application Area:DNA quantitation

"The nanodrop one is easy to use and replicates prove it’s accuracy and reproducibility. We have encountered some hiccups in the software where it will freeze, but a restart solves the issue. Simply download the results to a thumb drive and view them on any computer with the software."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Brigham & Women's Hospital



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
A Huge Improvement over the Nanodrop 1000
Rating: 5.0

  • Application Area:Analyze nucleic acids in various sample types.

"We've greatly enjoyed the new NanodropOne, which was a huge upgrade from our 1000. We decided to take advantage of a trade-in offer because our old device was giving errors and was unable to be calibrated. Since day 1 with this new equipment, everything has been easier. All the steps have been streamlined and it is beyond user-friendly. While we had both devices, I ran a few samples on both. While the 1000 had trouble giving consistent reads, the One can accurately measure the same sample with ease. If I had to pick one "fault" with this device, it's that I fear the touch screen could have issues down the road. That is the biggest change, as the old device was attached to a computer. We've had no issues at this point, but in my experience, the screens are usually the first to go. That being said, I don't expect any issues in the immediate future and I feel those issues are to be expected overtime. Overall, we are thrilled with this new equipment and would purchase again."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: R&D Biotech Company



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Excellent Instrument, even better customer care!
Rating: 5.0

  • Application Area:DNA/RNA quantification

"We've been very happy with our NanoDrop One. It's been a great friend to us in the lab! What we've been most impressed with, however is how responsive Thermofisher has been in all of our troubleshooting and technical support needs. Even minor issues with the machine were addressed promptly over the phone and email with excellent follow up. When we needed to send the machine out for repair, we were provided a loaner instrument and all of the shipping supplies promptly which enabled us to continue experiments without any disruption to workflow. We always had a direct line to someone for any follow up concerns or needs. Highly recommend!"

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Peprotech INC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Essential instrument for our lab.
Rating: 5.0

  • Application Area:protein concentration

"We've been using the Nandrop since it came on the market and the Nanodrop One has offered us a smaller footprint and an easy to use format."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: RTI International



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
Very happy with the NanoDrop One
Rating: 4.7

  • Application Area:Protein and DNA concentraion determination

"Overall very happy with the NanoDrop One. We had a few hiccups with software crashing at first but customer service quickly addressed our issue and there is not been a problem since. The small footprint is very nice and the instrument performs exactly as we need. Being able to easily transfer data via a thumb drive is a nice feature."

Review date: 14 Dec 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: University of Pennsylvania



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Good instrument.
Rating: 5.0

  • Application Area:Analyse protein and DNA concentration

"This is a truly plug and play instrument. No additional parts or equipment is required. Easy to use, accurate enough for our applications. A presence of the Cuvette option makes it an ideal choice ."

Review date: 30 Jun 2017 | Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi

NanoDrop One/NanoDrop OneC spectrophotometers Features:

    an ergonomic, standalone design with integrated Android tablet, eliminating the need for a separate computer and providing seamless data transfer via Wireless (if available), Ethernet or USB. Multi-sample processing is streamlined with Auto-Measure and Auto-Blank functions. Because of its wider dynamic range using auto-range pathlength technology, no dilutions are necessary for highly concentrated samples. The Acclaro technology enhances user understanding of sample quality while delivering accurate quantitative measurements.


    Features:

    • Wide spectral range (190-850 nm) for measuring a variety of samples types
    • Combining the proprietary sample-retention system with cuvette capability accommodates low and high concentrations
    • Pedestal measurements that require only 1 – 2 µL of your sample and do not require sample -dilution, even for highly concentrated samples
    • Calculates sample purity ratios (A260/A280 nm and A260/A230 nm)
    • Pre-configured methods for DNA, Protein A280, Microarray, Protein and Labels, Pierce 660, Bradford, BCA, and Lowry
    • User-friendly software includes custom methods and data export capabilities

Product Overview

Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi by Thermo Fisher Scientific product image

Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi

Manufacturer Thermo Fisher Scientific

4.7 / 5.0 | 26 reviews