Thermo Scientific HyperSep Retain Polymeric SPE

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Versatile polymeric material for retention of polar and non-polar analytes

• Exceptional recoveries for polar and non-polar analytes
• High and consistent recoveries
• High capacity material
• Fast and easy sample preparation method development
• pH stable 0-14

HyperSep Retain PEP (polar enhanced polymer) is a high purity, highly porous polystyrene DVB material modified with urea functional groups to give balanced retention of polar and non-polar analytes. The problems associated with column drying in traditional silica-based SPE materials are eliminated when using this product. This material is ideal for the retention of neutral compounds, or mixtures of compounds of different functionalities.


  • Drugs and metabolites in biological fluids
  • Peptides in serum, plasma or biological fluids