The Stauro caproKit™ represents an ideal kinase profiling system to improve and support drug discovery projects. Protein kinases play a key role in the regulation of signaling cascades e.g. for cell proliferation, apotosis, or differentiation. Disruption in the regulation of these inter-connected networks are closely associated with diseases like neuronal disorders, cancer, or inflammatory reactions. As many protein kinases are proto oncoproteins or involved in oncogenic signaling a major component towards cancer treatment is the understanding interplay of different signaling cascades to aid in the development of effective therapies. Staurosporine is a natural product which was originally isolated from the bacterium Streptomyces staurosporeus. The interest in this alkaloid resulted from i...Read more
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