SpectraMax® M5 Multi-Mode Microplate Reader by Molecular Devices®

Manufacturer Molecular Devices®
4.4
/
5.0
  |  21 reviews
The upgradeable SpectraMax M5 Multi-Mode Microplate Reader comes with the standard five modes of detection with the upgrade option to add HTRF at a later time. Your applications, your modes, your choice. The SpectraMax® M5 Multi-Mode Microplate Reader delivers single mode reader performance in one multimode reader package. The dual monochromator optics allow the widest range of applications to be utilized for bioresearch and drug discovery applications, all without the need to change filters.Th... Read more


SpectraMax® M5 Multi-Mode Microplate Reader by Molecular Devices® product image
SpectraMax® M5 Multi-Mode Microplate Reader



Average Rating: 4.4
21 Scientists have reviewed this product

5 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2017

  • Organization: Enamine



  • Ease of use
    5 out of 5
    After sales service
    2 out of 5
    Value for money
    1 out of 5
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Great when it is new
Rating: 2.7

  • Application Area: Cell toxicity

"As everything, Spectramax is "flexible and reliable" when it is new, but makes errors after it is "refurbished"."

Review date: 08 Feb 2017 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Zydus Cadila



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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good software support
Rating: 5.0

  • Application Area:cell based assays and ELISA

"The product is working fine with good software support. As the after sales are based in India it helps with any technical query."

Review date: 24 Nov 2015 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: New York Genome Center



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0

  • Application Area:Measure concentration of DNA & RNA samples

"The Spectramax always produces consistent and reliable results."

Review date: 11 Nov 2015 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Humboldt State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0

  • Application Area:Multi-function Plate Reader

"This multi-function plate reader is in our core lab facility. It is used by students in both classes and research. The flexibility of application is really a benefit for our University."

Review date: 16 Oct 2015 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Advanced Reviewer

  • Member since: 2013

  • Organization: SR-UAB



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Rating: 4.7

  • Application Area:Analyze: Kinetics, Endpoint Assay, Fluorescence, Absorbance, and Luminescence

"SpectraMax® M5 Multi-Mode Microplate Reader is very good and reliable system for any kind of assay (Kinetics, Endpoint Assay in Fluorescence, Absorbance, and Luminescence). This system doesn't need to change the filter for fluorescence just select excitation and emission wavelength and read the plate. I am using this plate reader very frequently and recommend to anyone looking for good plate reader. "

Review date: 10 Jul 2015 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: MUSC



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Rating: 4.0
"The M5 has been a versatile instrument and is being used for ELISA assays, fluorescence measurements and other types of studies. The data is stable and the instrument is generally reliable. The only problem is the that cost of the service contracts is very high. "

Review date: 10 Jul 2015 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Advanced Reviewer

  • Member since: 2012

  • Organization: Research



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Rating: 4.7

  • Application Area:hTRF assay,ELISA,

"This multi-mode plate reader is very easy to use and the software installed in this instrument can be used with any type of curve fitting applications. Our lab uses this product for cell based functional assays, ligand binding assays, immunoassays, etc. They can be used for many detection systems - absorbance, fluorescence, etc."

Review date: 05 Aug 2014 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Expert Reviewer

  • Member since: 2015

  • Organization: university of cambridge



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Rating: 4.3

  • Application Area:Proteomics

"This is a brilliant product. Easy to use and the software is also very user friendly. A lot of information can be obtained at the same time and offers diverse applications. It is fast and very accurate."

Review date: 24 Dec 2013 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Auburn University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Rating: 4.7

  • Application Area:Biochemical assay

"We have been using this for 3 years. It is easy to use and flexible. But it does have a well-to-well variation on 384 well plate when fluorescence intensity is measured. It also has a precision problem when 384 well plate was used. The signal goes down as the number of measurements are increased. The measurement with 96 well plates is OK."

Review date: 15 Jan 2013 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2013

  • Organization: Ra Pharmaceuticals



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Rating: 4.3

  • Application Area:Drug Discovery

"Software is very easy to use although it does occasionally malfunction and needs to be shut down and restarted. The %CV across the plate is minimal and machine works quickly so that's always a plus. With many features, it is used quite a lot in our lab and we are purchasing another one this year."

Review date: 13 Jan 2013 | SpectraMax® M5 Multi-Mode Microplate Reader


  • Status:

    Reviewer

  • Member since: 2012

  • Organization: Epizyme, Inc



  • Ease of use
    4 out of 5
    After sales service
    2 out of 5
    Value for money
    3 out of 5
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Rating: 3.0

  • Application Area:Luminescence assays

"Great software with easy analysis tools. It's easy to move and set-up. However, the technical service is slow and not very efficient."

Review date: 01 Mar 2012 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: Nanjing Agricultural University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0

  • Application Area:life science

"I like this machine as it can read samples with very large absorbance (more than 3), some other machines can only read less than 3."

Review date: 03 Feb 2012 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Panjab University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Rating: 4.7

  • Application Area:enzyme activities analyses

"The Spectra Max is a user friendly, sensitive and multi-application plate reader. It saves time, it’s fast and also allows multiple estimations at one site. I recommend it strongly for estimations of enzyme activities of various enzymes like Cox 2 by using kits."

Review date: 25 Jan 2012 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: National Institutes of Health



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Rating: 4.7

  • Application Area:ELISA

"An excellent system."

Review date: 24 Jan 2012 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: MUSC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0
"A versatile system with excellent software."

Review date: 05 Dec 2011 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2008

  • Organization: Selcia



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
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Rating: 4.3
"This system is easy to use and the data is transferable. There is a flexible assay format, and it is great to have multiple reading modes in such a small footprint."

Review date: 28 Sep 2011 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: Enamine Ltd



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Rating: 4.3
"An excellent, versatile monochromater-based plate reader. Can cover most cell-based and biochemical assays. Robust and reliable, easy to use with the SoftMax software from Molecular Devices."

Review date: 19 Sep 2011 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: UNIV. OF FLORIDA



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0
"We use it regularly and it's worth the money."

Review date: 05 Jul 2011 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2011

  • Organization: University of California San Diego



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0
"It is the best multifunctional reader with open-ended applications and extremely powerful SoftmaxPro statistical software. Patented Pathcheck and water constants are added features leading to most reliable and reproducible results. Easy to input any manufacturer's plate configurations for repeatability. I highly recommend this and other plate readers from Molecular devices for any start-up laboratory."

Review date: 03 Jun 2011 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2008

  • Organization: Selcia



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Rating: 3.7

Review date: 18 May 2009 | SpectraMax® M5 Multi-Mode Microplate Reader
  • Status:

    Reviewer

  • Member since: 2007

  • Organization: Invitrogen



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Rating: 3.3
"Flexible and reliable."

Review date: 06 Jun 2007 | SpectraMax® M5 Multi-Mode Microplate Reader
The upgradeable SpectraMax M5 Multi-Mode Microplate Reader comes with the standard five modes of detection with the upgrade option to add HTRF at a later time. Your applications, your modes, your choice.

The SpectraMax® M5 Multi-Mode Microplate Reader delivers single mode reader performance in one multimode reader package. The dual monochromator optics allow the widest range of applications to be utilized for bioresearch and drug discovery applications, all without the need to change filters.

The SpectraMax M5 Microplate Reader is the standard for UV/visible multi-mode reader absorbance, providing ultrafast, full spectral range detection for cuvettes, 96-, and 384-well microplates.

The SpectraMax M5 Microplate Reader possesses the five modes preferred by the majority of our users providing the benefit of multiple detection modes in one platform:

  • UV-Visible Absorbance (Abs)
  • Fluorescence Intensity (FI)
  • Time-Resolved Fluorescence (TRF)
  • Fluorescence Polarization (FP)
  • Glow Luminescence (Lumi)

SpectraMax® M5 MultiMode Microplate Reader Features:

  • Dual monochromators allow users to target the optimal assay excitation and emission wavelengths and eliminate the need to change expensive band pass filters between experiments.
  • Dual photomultiplier tubes (PMTs) provide detection flexibility to the widest variety of assays.
  • Reference diodes automatically adjust to slight fluctuations in excitation intensity to reduce measurement noise.
  • Absorbance applications are enhanced using top-quality UV grade fibers to provide strong light transmission in the lowest wavelengths.

Product Overview

SpectraMax® M5 Multi-Mode Microplate Reader by Molecular Devices® product image

SpectraMax® M5 Multi-Mode Microplate Reader

Manufacturer Molecular Devices®

4.4 / 5.0 | 21 reviews