When working with model membrane systems. Receptor anchored in membrane-like environments interacting with analytes in aqueous buffer. Lipid monolayers ineracting with membranebinding biomolecules. Direct hydrophobic adsorption of a ligand (to mimic Elisa).
Sensor Chip HPA Applications:
Suitable for the study of membrane-associated interactions
Incorporates an interaction partner associated with membrane surfaces into a monolayer to enable interaction analysis
User-prepared liposomes adsorb spontaneously to the hydrophobic surface to form a supported lipid monolayer with the hydrophilic “heads” directed out toward the solution