The scalable energy of the S-series systems processes various volumes and masses in seconds. Sample integrity is maintained as the Covaris process is non-contact (for example, no evaporation or probe contact) and non-ionizing. As the process occurs in a closed vessel, there is no cross-talk between samples. Additionally, closed tube processing allows head-space modification, such as a biochemically inert gas for labile molecules. Isothermal, reflux processes from 4ºC to 40ºC are standard.
Broad Range of Applications of the Covaris S-Series:
• Tissue disruption and homogenization
• Sample extraction for metabolic and proteomic profiling
• DNA shearing
• Chromatin shearing
• RNA extraction
• Cell lysis
• Compound dissolution
• Compound formulation
• ADME/Tox
Covaris S2 is used in most applications. We may recommend other S-series models for certain specialized projects. S-series instruments may also be integrated into robotic systems for enhanced automation. Please contact Covaris for further details. The standard S-series configuration uses a borosilicate culture tube with polypropylene screw-top closure. Additionally, the process enables tubes to have surface modifications for special applications (e.g., parylene or silane coating).
Our proprietary software, SonoLab™, runs on Windows® XP with easy-to-use-tools. The system may also be configured for ActiveX control.
The bench-top size system is approximately 21 cm wide, 31 cm high and 52 cm deep. The unit includes a notebook computer and, if required, a chiller may be readily attached.