Three formats are available for the isolation of RNA from animal and plant tissue, cultured cells, and bacteria. Both AquaPure RNA isolation kits use a unique salt-precipitation procedure in a scalable, aqueous reagent-based protocol. The Master Blaster RNA extraction kit utilizes a monophasic solution of phenol and a chaotropic agent in an improvement to the single step isolation of total RNA developed by Chomczynski and Sacchi (Anal. Biochem. 162, 156-159, 1987). Both methods enable RNA to be quickly and effectively isolated for immediate availability in downstream applications, including RT-PCR and northern blots.