QTRAP® 6500 LC-MS/MS System by SCIEX

"Amazing sensitivity with rugged behavior. The ion drive source is able to cope with high flows (1mL/min) in a very efficient way. Extremely fast dwell times and settling times for multicomponent analysis."

"Really useful tool for biopharmaceutical application as the sensitivity and LDR is outstanding in this system."

"Good in robustness, in method and easily handles huge data for analysis."

"The sensitivity of the instrument is incomparable with most of the other competitors and service support is already well noted in the industry. The current version of the analyst software also has a superior quality compliance with respect to CFR Part 11. As the industry is moving to micro formulations and biosimilars the betterment in sensitivity."

"The system was used for the quantification of putative biomarkers in complex background (e.g. serum or tissue homogenate). Coupled to a microLC and equipped with a special probe for the IonDrive Turbo V Source, which allowed to run the system at 6 ul/min, highly reproducible results for the quantification of up to 100 proteins per run were achieved. The Turbo V Source was clearly favoured by everybody over the nano spray source."

"I developed a method of natural folate as well as synthetic folate analysis employing a Sceix 6500 mass spec. The sensitivity and the stability of the system let me develop a very sensitive method of folate vitamer analysis in food and supplements accurately and precisely to label the products in compliance to the new labeling regulations by FDA as Dietary Folate Equivalents. I would not have been able to develop the method without the sensitivity and the stability afforded by this mass spec."

"Instrument is easy to use and give high quality results with high throughput samples."

"6500 Qtrap is easier to use and we get reproducible results. Instrument performance is faster and more sensitive compared to earlier Sciex instruments such as 4000 Qtraps"

"We were able to achieve highly satisfactory results with high sensitivity, selectivity and reproducibility. Technology platform operation was seamlessly smooth and was not challenging to train new team members. Considering the quality MS/MS data from our HTS targeted proteomics studies we deployed two additional 6500 QQQ MS, the after sales-service has been very promising and since over a year we have not encountered any instrument breakdown issues, very rugged instrument. I would be glad to deploy this state-of-the-art technology for future upcoming large molecule related projects and highly recommend it based on my experience."

"I had used this instrument after a Phase I and II metabolic incubation with S9 at different time point and with a single injection using an acquisition correlated with a dependent fragmentation I was able to determine with six injections all the metabolite profiling both for kinetic parameter and Metabolite Identification. A really robust instrument with powerful software."

"Just purchased one, the instrument is excellent. They have improved the software making it even better than before. It has high sensitivity and good selectivity fully integrated, the reproducibility is also much better. You can dilute more to a lower matrix effect, but I still recommend clean up steps as they are always necessary! The QTRAP comes with some good metabolite ID Light Sight and its linear dynamic range is very good. Overall it is excellent for residue analysis and metabolism studies. In particular there are many advantages to this system if you do TOX, residue, environmental fate, screening, etc. I highly recommend you get one."

"Best sensitivity and robustness for that class of instruments. Very good servicing. Works well with Eksigent MicroLC."

"Excellent versatility towards other types of ion sources or other modifications. It is sensitive and robust. Maintenance of this machine is quite easy."

"Very informative and beneficial. Good experience for knowing about the analytical chemistry. Very good."

"QTRAP 6500 is a great product with great features and value for money. Their customer service is exceptional."

"This is the ideal triple quad instrument for identification and quantification of analytes at very low level."