Pseudoprolines


EMD Millipore, a division of Merck KGaA, Darmstadt, Germany

Pseudoproline dipeptides are undoubtedly the most powerful tools described to date for enhancing synthetic efficiency in Fmoc SPPS. Novabiochem® now offers 28 pseudoproline dipeptides - represent...read more

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Description

 

Pseudoproline dipeptides are undoubtedly the most powerful tools described to date for enhancing synthetic efficiency in Fmoc SPPS. Novabiochem® now offers 28 pseudoproline dipeptides - representing the widest selection on the market today

The routine use of pseudoproline dipeptides has been found to:

  • Avoid costly and unnecessary repeat syntheses of failed sequences
  • Increase purity of crude products
  • Simplify HPLC purification
  • Increase yield of crude and purified products
  • Enable syntheses to be carried out on a lower scale
  • Make possible racemization-free fragment condensation of C-terminal Thr- and Ser- containing peptide sequences

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