Pseudoproline dipeptides are undoubtedly the most powerful tools described to date for enhancing synthetic efficiency in Fmoc SPPS. Novabiochem® now offers 28 pseudoproline dipeptides - representing the widest selection on the market today
The routine use of pseudoproline dipeptides has been found to:
Avoid costly and unnecessary repeat syntheses of failed sequences
Increase purity of crude products
Simplify HPLC purification
Increase yield of crude and purified products
Enable syntheses to be carried out on a lower scale
Make possible racemization-free fragment condensation of C-terminal Thr- and Ser- containing peptide sequences
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