The Stable Alternative to C8 or C18 Columns Hamilton PRP-1 (Polymeric Reversed Phase) HPLC columns combine the best characteristics of silica-based and polymeric columns to arrive at a column that is highly inert and long-lasting. Quality assurance as well as research and development laboratories find that PRP-1 columns last significantly longer than silica-based C8 or C18 columns. This is particularly true for difficult analyses like: high pH samples (pH 8-13); labile or reactive samples (irreversible adsorption); high aqueous purifications (80-100% water); and separations with ion pairing reagents.
PRP-1 Columns are beneficial in a number of ways:
Wide pH Stability Stability from pH 1 to 13 allows for the analysis of samples at high pH (8-13) without the possibility of column degradation or loss of efficiency. An expanded pH range also allows samples to be chromatographed while ionized. This greatly enhances the detectability of some samples.
"Very stable, easy to condition column that stands up to every application of nucleic acid purification. Four stars for service since I have not needed any."
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