ProteOn liposome capturing kit for capturing lipid assemblies such as liposomes on a hydrophilic chip surface through DNA hybridization.
The ProteOn liposome capturing kit includes 1 ProteOn LCP sensor chip, 1 ProteOn LCP capturing reagent kit, and the ProteOn lipid modification conditioning solution. It is capable of capturing lipid assemblies such as liposomes on a hydrophilic chip surface through DNA hybridization.The LCP sensor chip surface is functionalized with NeutrAvidin in a planar con... Read more
ProteOn™ Liposome Capturing Kit
ProteOn liposome capturing kit for capturing lipid assemblies such as liposomes on a hydrophilic chip surface through DNA hybridization.
The ProteOn liposome capturing kit includes 1 ProteOn LCP sensor chip, 1 ProteOn LCP capturing reagent kit, and the ProteOn lipid modification conditioning solution. It is capable of capturing lipid assemblies such as liposomes on a hydrophilic chip surface through DNA hybridization.
The LCP sensor chip surface is functionalized with NeutrAvidin in a planar configuration that is formed on a self-assembled monolayer. The ProteOn LCP reagent kit activates the chip surface by a biotinylated DNA tag so that the chip is able to capture DNA-labeled lipid assemblies through DNA hybridization. The reagent kit attaches DNA tags to the liposomes in order to anchor them to the chip surface. It is possible to capture two or more layers of lipid assemblies for additional sensitivity. This method of capturing allows interaction analyses involving lipid membranes or membrane proteins embedded in intact lipid assemblies.
Benefits:
The ProteOn liposome capturing kit includes 1 ProteOn LCP sensor chip, 1 ProteOn LCP capturing reagent kit, and the ProteOn lipid modification conditioning solution. It is capable of capturing lipid assemblies such as liposomes on a hydrophilic chip surface through DNA hybridization.
The LCP sensor chip surface is functionalized with NeutrAvidin in a planar configuration that is formed on a self-assembled monolayer. The ProteOn LCP reagent kit activates the chip surface by a biotinylated DNA tag so that the chip is able to capture DNA-labeled lipid assemblies through DNA hybridization. The reagent kit attaches DNA tags to the liposomes in order to anchor them to the chip surface. It is possible to capture two or more layers of lipid assemblies for additional sensitivity. This method of capturing allows interaction analyses involving lipid membranes or membrane proteins embedded in intact lipid assemblies.
Benefits:
- Hydrophilic surface for high data quality
- Low nonspecific binding for high data quality
- Good regenerability for low chip-to-chip variability and costs
- Stable capturing of lipid assemblies for high data quality
- Capturing or “building” multiple liposome layers for high sensitivity in difficult applications
- Array of 6 x 6 interactions for efficient experiment optimization and high throughput
Product Overview
