The ProteoMass Guanidination Kit allows you to increase MALDI-MS sensitivity, increase sequence coverage, and identify with greater confidence. Peptides generated during proteolytic digestion with C-terminal Arginine residues are ionized preferentially over peptides wtih C-terminal Lysine residues, leading to compromised sequence coverage and limited confidence during peptide mass fingerprint analysis.
The ProteoMass Guanidination Kit efficiently and conveniently converts C-terminal Lysine residues to homoarginine, increasing MALDI sigma strength and producing enhanced sequence coverage.Features and Benefits:
- Identify more samples with greater accuracy and confidence
- Increase throughput and save time - only 35 minutes to use the kit vs. 2 hours using traditional methods
- Compatibility - compatible with 1D or 2D PAGE gel bands or spots, as well as complex cell extracts