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Bruker Daltonics Introduces New Proteineer Tools for Expression Proteomics: Proteineer-LC system and Top-Down Proteineer  

Proteineer-LC combines multi-LC-MS/MS proteomics approaches, e.g. using ESI ion trap mass spectrometry, with a new optimized sample splitting and MALDI fraction collection device, called Proteineer-FC. This enables a seamless LC-MALDI-MS/MS proteomics workflow with our TOF/TOF systems at high sensitivity, using our patented Anchorchip sample plate technology.

Information-dependant workflows can be utilized so that tentative protein IDs can be confirmed in an intelligent, results-driven way by our WARP-LC(TM) software. WARP-LC can analyze LC-MS(n) results from our HCTplus high capacity ion trap on the fly and then direct targeted MALDI-TOF/TOF experiments, based on the initial database search results. The combined information significantly increases ID success rates, allows identification of lower abundance proteins and enables further PTM characterization without LC time constraints using the LC-MALDI-TOF/TOF workflow.

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