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Member since: 2014
Organization: NP Analytical Labs
Application Area: Food and Agriculture
"We have had good luck with the Shimadzu Prominence XR systems in our lab. Systems are easy to use and control via an ethernet connection. Our service engineer has done great work for us, so I would recommend their service. The Prominence XR has been a good, lower-cost alternative to the true UHPLC systems available, allowing us to reach higher pressures (~ 9600 psi) without the much higher cost of the UHPLC. In summary, I would say that the Shimadzu HPLC's have given us excellent quality and good value. (Disclaimer: The views expressed above are my personal opinions and do not necessarily reflect the views of my employer.)"
Member since: 2006
Organization: Purificacion y Analisis de Fluidos Ltda.
"A very useful alternative to develop fast analysis by HPLC with no extreme pressure. With Prominence XR it is possible to reduce the time analysis and solvent consumption with a conventional HPLC that can run traditional and fast LC."
Utilizing features of the Prominence UFLC, which offered high speed as well as high analysis accuracy and reliability, thereby increasing analysis cost-efficiency, we have developed the Prominence UFLCXR, which achieves greater data quality by means of higher separation performance.
While maintaining the high analysis accuracy and reliability cultivated with the Prominence series by using a high-speed separation column and optimizing the system, we have increased separation performance to a level greater than that of conventional LC.
The ability to reliably perform the high-separation, high-sensitivity detection of trace compounds is required. Improving separation performance by simply increasing the column length also increases the analysis time, which reduces analysis efficiency.
With the Prominence UFLC, high-speed analysis while maintaining a high degree of analysis accuracy and reliability is possible and with the Prominence UFLCXR, greater separation performance is attained. In order to achieve the ultimate in high separation performance, column efficiency has been improved by optimizing the balance between the particle diameter of the XR-ODS and XRII-ODS high-speed separation column and the column length, and the system has been optimized to attain the highest possible level of column performance.
The combination of the Prominence UFLCXR and a Shim-pack XR-ODS II column (length: 150 mm) achieves a level of separation performance equivalent to that of at least a 250-mm column containing packing material with a particle diameter of 5 µm. The wide dynamic range of the SPD-20A detector enables the high-separation, high-sensitivity detection of fine peaks, such as those obtained for minute quantities of impurities in pharmaceuticals, and thereby enables highly reliable analysis in which the slightest presence of impurities is not missed. Also, the low-carryover SIL-20AXR autosampler supports high-accuracy analysis.
Prominence UFLC-XR Features: