The PowerClean® DNA Clean-Up Kit provides a quick, easy and reliable secondary clean-up method to purify previously isolated genomic DNA from any source for all downstream applications. Problematic isolated DNA from soil may be amber to brown in appearance, which is an indicator of PCR inhibiting substances, like humics and polyphenols. Even colorless samples may contain PCR inhibitors which can be cleaned up with this kit. A high level of purity is achieved which allows for more successful PCR amplification from a variety of problematic samples.