Status:
Expert Reviewer
Member since: 2010
Organization: D. Y. Patil Institute of Pharmaceutical Sciences
-
- Ease of use
- After sales service
- Value for money
"PolyBlock PB4 is ideal and best suited for pharmaceutical applications in terms of flexibility and upgradability for various applications. For such applications like: pH monitoring and control, solubility and MSZW for crystallisation, high Pressure Hydrogenation, Online Real Time calorimetry, reflux & inerting, PAT tools in future, overhead motor stirring, and extended temperature range 80 to 250 (depends on the chiller being used with the PB4)."
Review date: 10 Nov 2014 | PolyBlock
Key features:
- 4 or 8 Independent reaction zones
- Independent temperature control (100 °C difference between zones, temperature range of -40 °C to +200 °C)
- Independent agitation control (250 to 1500 rpm, suspended mechanical or overhead stirring available)
- Small footprint – no larger than a typical laboratory notebook
- Use any combination of reaction vessels on one platform
- Intuitive control software with a choice of interfaces
Designed to maximize your laboratory’s productivity, parallel synthesis technologies with PolyBLOCK is an easy-to-use, flexible, and compact multi-reactor system.
With either four (PolyBLOCK 4) or eight (PolyBLOCK 8) independently controlled and monitored zones, PolyBLOCK 4 offers working volumes of up to 500 ml and PolyBLOCK 8 up to 120 ml. Reactor options range from 1 ml HPLC vials to round or flat-bottom flasks up to 250 ml and custom reaction vessels up to 500 ml.
Agitation in each zone is independently controlled and temperature monitoring and control is offered with either reactor and/or zone temperature.
Temperature control
- Ambient to 200 °C (without external circulator, software limited).
- Options to decrease the range down to -40 ⁰C (circulator dependent)
- Separate mantle around each reactor allows the temperature to be controlled individually, with a range/difference of over 100 °C between the reactors
Independent stirring
- Indirect agitation with magnetic stirrer bar as standard.
- Suspended mechanical agitation for efficient mixing on small-scale and non-viscous samples.
- Optional Overhead direct agitation for larger vessels.
Intelligent software control and analysis
- Control software enables regular data logging, multi-step recipes, parameter control, and feedback loops.
Safety features
- Include automatic user-configurable reaction detection and shutdown procedures, to ensure user safety.
- Automatic hardware and software fail-safes are installed on every system.
Condensing options
- Easy quick-connect solution for condensing and inerting in larger reactors. Seals allow condensers to be removed without cooling liquid spillage.
- Also available reflux and inerting block, with adapters for vials, tubes, and reactors
Reactor options
- Vessel types are available in Glass, Stainless Steel, or Hastelloy. With reactor volumes up to 500 ml.
- High Pressure and Vacuum Systemsavailable, more details on our high-pressure system can be found via PolyBLOCK High Pressure.
- Sampling Systems through active pumps, manual dip tubes, automated level control, or multisampling units, like the ASU.
- Reagent Addition through fully automated liquid and gas feeds as well as volumetric syringe pumps. These solutions can be applied to both high and low-pressure systems.
- Control Options all relevant inputs can be logged, enabling automated monitoring and, where appropriate, feedback control of the reactor system.
- Sensor Options
- Temperature, pressure, pH, turbidity, conductivity.
- Integration of third-party probes is possible, such as in-situ FTIR, particle sizing probes and Raman probes.
Product Overview
