PathDetect Trans-Reporting Systems



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The PathDetect in vivo signal transduction pathway trans-reporting systems are designed for specific, rapid, and convenient assessment of the in vivo activation of transcription activators and upstream signal transduction pathways. The systems are useful for identifying whether a newly cloned gene is involved in a signal transduction pathway, and if so, at which step of the pathway.


  • Identify specific stimuli that leads to the phosphorylation of a test transcription factor
  • Easier and faster than Western blotting or gel-shift assays
  • Sensitive, quantitative assays
  • Stable cell lines available for constitutive expression of CREB, Elk1, and CHOP