The PathDetect in vivo
signal transduction pathway trans-reporting systems are designed for specific, rapid, and convenient assessment of the in vivo
activation of transcription activators and upstream signal transduction pathways. The systems are useful for identifying whether a newly cloned gene is involved in a signal transduction pathway, and if so, at which step of the pathway.
- Identify specific stimuli that leads to the phosphorylation of a test transcription factor
- Easier and faster than Western blotting or gel-shift assays
- Sensitive, quantitative assays
- Stable cell lines available for constitutive expression of CREB, Elk1, and CHOP