P-series depth filter sheets and modules were developed for the strict requirements in biotechnological and pharmaceutical industries. For many years, manufacturing has been carried out and stringent in-process control methods in line with the requirements of the pharmaceutical industry. This assures constant high filtration quality as well as a very high purity of the filter medium, both features our customers benefit from.
The P-series depth filter sheets and modules are available in 10 different types. Due to specific manufacturing methods the distinguishing feature of the P-series is high purity resulting in a very low release of extractables. The depth filter material has been especially optimized to provide a very low release of endotoxins (< 0.02 EU/mL after flushing with 50 L/m2 WFI).
The filter matrix especially developed for the P-series assures retention rates down to 0.1 µm and thus enables an optimal pre-filtration of biological products like no other depth filter for the protection of downstream process steps.
Due to their electrokinetic adsorption potential, positively charged resins increase the retention of smallest particles, such as whole and crushed cells, cell lysate components, endotoxins, DNA and viruses, which usually are negatively charged. Pall P-series depth filters are used worldwide in biotechnological and pharmaceutical applications and provide reliable and economical filtration.
Features and Benefits
Low unspecific protein binding
High dirt hold capacity
Good membrane protection
Long life time
Well graded sheets over the entire range
P-grade sheets and Supradisc modules are steam sterilizable at 125 °C (257 °F) for 30 minutes
All plastic components used in constructions meet the specifications for the biological test listed in the current version of the USP class VI 121° C
All P-grade depth filter sheets used in constructions meet the specifications for the biological test listed in the current version of the USP class V 121 °C
P-grade sheets in sizes > 400 x 400 mm (16 x 16 in.) and Supradisc modules as well as all their components are fully traceable