Oasis® µElution Plate by Waters

"The Oasis µplate was used as sample preparation for LC TOF application in order to get a valid concentration determination. The product was very easy to use and produced reliable results and good quality."

"The PRIME HLB microElution Plate is a great apparatus for the Solid Phase Extraction technique. I used it to concentrate my metabolites of interest in rat urine samples, and it worked perfectly. But, it didn't work as effectively while concentrating the same metabolites in mice plasma samples. I believe the reproducibility across species (rats vs mice) and the kind of biological samples (plasma vs urine) is low. I would like to see better optimization of the apparatus."

"After evaluating many of the SPE products currently on the market on the criteria of recovery, matrix cleanup, ease of use, and cost, Oasis PRiME HLB uElution plate by far is the best option for the analysis of drugs of abuse in whole blood samples. Waters provided excellent support through application notes, in-person training and method development, troubleshooting, and equipment support throughout the optimization and validation process. The uElution plates demonstrate excellent reproducibility, recovery, and matrix cleanup, even with a complex matrix such as whole blood. The 96-well plate form factor will support a lot of scalability for our lab as we receive additional samples, and the Waters positive pressure manifold makes sample processing extremely easy and rapid. Overall, a great system for tricky analytes and matrices!"

"We are using the Oasis HLB µElution Plate 30µm for our Porphobilinogen analysis in urine and the Oasis MCX µElution plate for our LysoGb3 analysis in urine, on our metabolic lab. We have a manifold voor the extraction system, also from Waters. We use it to concentrate the components to detect them on our Waters Micromass Quattro Micro. We are performing this analysis for a few years now and it gives great results for us. The lysoGb3 analysis is in nmol/l. So the limit of detection is very good for us. We had a private workshop on our lab by some employees from Waters to show us how it all works. So we are satisisfied with it! The plates are not cheap, but they work for us!"