Nytran SuPerCharge (SPC) nylon membranes have a very high positive charge. Improvements in the manufacturing process result in a membrane with a higher density of nylon per unit area. The Increased charge and greater nylon density provide increased binding sites for your samples.
Consistent membrane morphology Standard nylon membranes show a wide range of pore sizes. Nytran SuPerCharge membrane uniform pore size (0.45 µm) and pore distribution leads to greater reproducibility of results across a membrane and from blot to blot. Scanning electron micrographs of Nytran SuPerCharge and typical nylon membranes reveal the consistency of this new membrane.
Low background Poor signal to noise ratios have been associated with positively charged membranes in the past, particularly in association with chemiluminescent detection. Whether using radioactive or non-radioactive detection techniques, Nytran SuPerCharge consistently gives a high signal with extremely low background.