Noviplex™ Cards Plasma Sample Collection Tool by Shimadzu Corporation

Shimadzu Scientific Instruments has partnered with Novilytic Labs to offer a powerful, new technology for the rapid generation of plasma from whole blood.

NoviplexTM is a simple, powerful tool used to collect a volumetric sample of plasma (2.5 µL) from a non-volumetric application of whole blood in just minutes. An un-measured application of between 20 to 75 µL of whole blood from a finger-stick, mouse tail-bleed (or other source) is all that is required to collect a volumetric plasma sample. Noviplex can be used as a single step, solid-phase method for sample preparation and analyte extraction, eliminating the need for time consuming techniques such as solid phase extraction, centrifugation and evaporation.


Noviplex™ Cards Plasma Sample Collection Tool Features:

• 99% removal of red blood cells (based on Hb levels in plasma).
• Plasma sampling volumes of 2.5 µL.
• Inter-card CV of ~1% in plasma collection volume at constant hematocrit (HCT).
• Inter-card CV of 2% collection volume variation with 20% to 71% HCT
• Proteins are deposited as a monolayer upon drying.
• Metabolites are present in the protein monolayer.

Advantages:

• Rapid sample preparation for MS-based analysis, while maintaining assay reproducibility and selectivity.
• Volumetric plasma sample collection using a single drop of whole blood.
• Specimen volumes as low as 25 µL.
• Noviplex cards simplify sample preparation. Eliminates need for solvent extraction, centrifugation and evaporation.
• Exceptional reproducibility independent of hematocrit.